The QFC Study is a visionary program of research that will undertake a view of the current health and wellbeing of families across Queensland to understand parental health, ageing and its impact on pregnancy outcomes. Its vision is to determine how a baby’s health and exposures in early life impacts the risk of disease development or being health and well later on in life. Families will begin their journey in the study during the antenatal period of their pregnancy and continue for many years sharing their life experiences of health, wellbeing, environmental exposures, social determinants of health, education and health-related events. These families will work alongside a consortium of researchers and health services who are all working to address disease at its roots and arm health professionals and policy makers with the evidence they need to improve health, wellbeing and other life outcomes in future generations. The diversity of our Queensland population is highly valued—as are each individual participants’ needs—which enables the QFC to recruit participant families who are; culturally and linguistically diverse, from the LGBTIQA+ communities, living in metropolitan, rural and remote communities, Aboriginal and Torres Strait Islanders and those who may have additional health needs.