26/11/2025
Understanding how genetics plays a major part in fertility and reproduction is very important. Many couples are completely unaware that their inability to conceive may in fact be from genetic, or hereditary issues that have not been screened for.
When it comes to fertility and not being able to conceive, more and more couples are now struggling. Some of this is due to increased stress levels, poor diet and lifestyle, increase alcohol consumption, lack of preconception care and many other factors.
However, one key area that is not often talked about, or even known to many is genetic factors, chromosomal factors, and DNA issues passed on through our s***m and eggs.
Fertility and reproduction is one of the hardest areas of medicine to understand.
No amount of “Dr Google” searching is going to bring answers for many couples and this is something that needs to be discussed more.
Unless you have done years of study and clinical research into fertility and reproduction, you just can't understand the finer details and intricacies of conception. Even then, some answers are just not available to anyone at this present time.
One of the biggest factors in embryos not developing, is genetic & chromosomal errors at the embryo stage. Even if both parents have normal karyotype (46XX and 46XY) it does not mean that they cannot produce random chromosomal & genetic errors in their s***m and eggs. The thing is, the older we get, the more these errors occur and the harder it is to fall pregnant.
Given that 1 in 22 couples are at risk of a hereditary gene mutation, it is really important to screen couples properly and not just do the basics. To date up to 6,000 single gene disorders have been characterized and it is estimated that 14 per 1,000 people suffer from one of these conditions. A person who inherits a mutation in a single gene will carry that mutation in every cell of their body.
There are many factors to fertility & reproduction and why it is important that couples see someone who is a qualified fertility expert. If you need help with being able to conceive, contact my clinic and find out how my fertility program can assist you. Contact info@drandreworr.com.au