03/12/2025
If radiant and vital skin is your goal, minerals need to be on your mind. Today the focus is zinc!
In mineral balancing we talk a lot about metalloenzymes. These enzymes (proteins) in the human body require particular metal ion cofactors to function (enzymes are biological catalysts that speed up chemical reactions in the body).
At least one third of all enzymes in the body are metallonezymes. Without these mineral cofactors most cells, tissues, organs and systems will not function optimally.
Zinc is a cofactor in over 300 metalloenzymes!
Back to the skin! Zinc plays a critical role in the health of our largest organ. If you do not have enough, it will show up on your skin. Reduced radiance and skin vitality may manifest but there may be more serious signs of a deficiency.
Enzymes in the skin such as the antioxidant enzyme superoxide dismutase SOD, matrix metalloprotinases MMPs essential for cell proliferation, alkaline phosphates and RNA/DNA polymerases essential for cell division rely upon zinc.
Keratinocyte (skin cells) in the epidermis are particularly hungry for zinc to support their proliferation, differentiation and control inflammation. The concentration of zinc is far higher in the epidermis than the dermis.
Fibroblast cells in the dermis also rely upon zinc for cell growth and protection from damage. Collagen and elastin synthesis as well as wound healing suffers without optimal fibroblast cell function.
Zinc plays a criticalĀ role in maintaining skin integrity. Inadequate zinc intake may manifest as skin issues like rashes, dryness, inflammation and slow wound healing. Nail issues may be present such as brittleness, ridging, and white spots.
Assessing the skin and hair quality may provide important clues to whether zinc is playing a role.
I personally like to use a properly sampled, analysed and interpreted HTMA and blood pathology (low alkaline phosphate enzyme in the blood can be a sign of low zinc as it is dependant upon it). Blood is a transport medium so serum zinc is not that reliable although may still have some value.