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Centenary Institute, Building 93 Missenden Road, Camperdown (2026)

19/02/2026

Researchers at Centenary plus collaborators have developed a new tool called the FAP-Index that could improve how doctors identify people at risk of severe liver scarring caused by metabolic fatty liver disease, a condition affecting around one in three Australians.

The FAP-Index combines a straightforward blood test with routine clinical information to give doctors a clearer picture of who needs further investigation.

Adding the FAP-Index to existing first-line blood test risk scores reduced uncertain results by up to 70 percent compared with current screening tools alone.

With new treatments for liver disease now becoming available, better early detection is more important than ever.

Read more: https://www.centenary.org.au/news/new-fap-index-could-transform-early-detection-of-severe-liver-disease/

19/02/2026

🏥 First‑of‑its‑kind AI platform to improve cancer treatment decisions 🏥

Centenary researchers have been awarded funding to commercialise a first of its kind medical AI platform designed to improve treatment decisions and reduce unnecessary surgeries for Australian cancer patients.

Cancer is Australia’s leading cause of disease burden, responsible for about 50,000 deaths each year and costing the health system over $10 billion annually. However, current guidelines misjudge patient risk in up to 40 per cent of cases, resulting in avoidable surgeries, unnecessary chemotherapy and preventable relapse.

PanaceAI aims to address this by providing precise, personalised risk assessments that show clinicians exactly which factors drive each recommendation.

Early studies involving more than 6,000 patients with colorectal polyps, thyroid cancer and mesothelioma have shown accuracy improvements of up to 32 per cent and a 25 per cent reduction in unnecessary thyroid operations.

Read more: https://www.centenary.org.au/news/firstofitskind-ai-platform-to-improve-cancer-treatment-decisions/

10/02/2026

This International Day of Women and Girls in Science, we celebrate some of the extraordinary up-and-coming female researchers at Centenary Institute— all driving discoveries that will change lives.

❤️ Yuchen Chang is investigating the genetics behind sudden cardiac death, so we can stop it striking young people without warning.

👁️ Dr Mojdeh Abbasi is engineering stem-cell-infused contact lenses designed to restore sight.

🧠 Dr Ka Ka Ting is helping pioneer a groundbreaking new treatment for Alzheimer’s disease.

🧪 Dr Lise Hunault is working to make lab-grown insulin-producing cells a lasting treatment for people with type 1 diabetes.

🫀 Dr Seaky Lim is creating tiny beating hearts in a dish to study heart disease and test future therapies.

🩸 Dr Aster Pijning is working towards new and more effective treatments for patients at risk of blood-clotting and bleeding disorders.

🧫 Dr Cindy Hsin-Yi Tseng is working to understand why men are more than twice as likely to die from melanoma compared to women.

🚑 Dr Manuela Florido is working on groundbreaking new ways to repair the heart after a heart attack.

Every one of these researchers is helping build a healthier future for our community. Today we celebrate their curiosity, vision and impact. 💛

05/02/2026

✨Researcher spotlight ✨

For 18 years, Associate Professor Richard Bagnall has been driving discoveries at Centenary that could save young lives. ❤️‍🩹

Joining us in 2008 as a research officer fresh from a PhD in molecular biology from King's College London and a 3-month round trip to Cape Tribulation in a camper van, Richard now leads our Centre for Cardiovascular Research. His work is fuelled by one mission: understanding why some young people die suddenly — and finding the answers hidden in our genes.

His pioneering approach in bioinformatics and genome analysis has been backed by major fellowships and NSW Health grants, helping build a team dedicated to uncovering life‑saving insights.

His advice to the next generation of scientists? “Take every opportunity that comes your way and give it a go. Even if it doesn’t work out exactly as planned, you’ll always learn something that becomes valuable later on."

Celebrating 18 years of impact at Centenary. 🎉

30/01/2026

For 40 years, our researchers have been driving breakthroughs that change lives — including game‑changing innovation in cancer care. 🎗️✨

We’ve developed a new compound that assesses the effectiveness of cancer therapies.

It holds the potential to open up the window of opportunity to change treatment options, switching patients to a more effective treatment and prolonging their life.

“Currently it takes around 6-12 weeks to see if a patient is responding to their cancer treatment,” says Philip Hogg, from Centenary and Adjunct Professor at the University of Sydney (Sydney Health). “This is too long to wait while the patient’s condition is deteriorating.”

“The new compound may allow assessment in the first two weeks of treatment, enabling clinicians to see whether a patient is responding to their therapy by measuring changes in the amounts of cell death in the tumour.”

This groundbreaking ability to clinically image cell death may allow a more accurate and rapid assessment than current approaches. It holds great promise for a number of cancers, with researchers currently focusing on gastrointestinal cancers, breast cancer and lymphomas thanks to generous support from Cancer Institute NSW.

It could prove to be life-changing, if not life-saving for millions of people. 💛

Explore more of our impact over four decades:
centenary.org.au/impact

21/01/2026

The Centenary Institute is deeply saddened by the passing of our Founding Patron, Professor The Honourable Dame Marie Bashir AD CVO.

A well-respected and much-loved figure in the Australian community, Dame Marie was a passionate advocate for the health sector and a valued supporter of our researchers.

As Founding Patron, she was a renowned advocate for scientific discovery, championing its vital role in improving health outcomes for the wider community. She took a keen personal interest in the Institute’s progress, its researchers and research programs.

Her legacy as a distinguished leader, health advocate and member of the Centenary community will be remembered with profound respect and gratitude.

We extend our sincere condolences to her family and friends.

Vale Dame Marie Bashir.

Read more: https://www.centenary.org.au/news/centenary-institute-mourns-the-passing-of-dame-marie-bashir/

05/01/2026

We are proud to share that Centenary Institute researchers have secured more than $3.3 million in NHMRC Ideas Grants to drive innovative research in gene therapy and liver disease.

Dr Chuck Bailey will lead a project focused on improving the safety and effectiveness of gene therapy, with the aim of enabling lower, safer doses for patients with rare genetic conditions. The approach will be assessed in a pre-clinical model of a debilitating muscle-wasting condition called Pompe disease.

Associate Professor Patrick Bertolino will lead research into how the immune system interacts with the liver. The work aims to guide the development of new vaccines for liver infections such as hepatitis and malaria, and support more precise treatments for chronic liver disease.

Congratulations to both scientists on their achievements and their commitment to research that could improve lives.

Read more: https://www.centenary.org.au/news/funding-boost-for-pioneering-gene-therapy-and-liver-disease-research/

05/12/2025

“Mum passed away just before midnight on New Year’s Eve 2024, two weeks after her 82nd birthday and one week after Christmas," says Imedla.

"As my brother and I left the care home, fireworks lit up the sky. It felt like the world was celebrating not just the new year, but her life — a life filled with love, strength, laughter and kindness.”

“I feel incredibly fortunate that Mum always remembered my name. Her eyes always lit up. And she always told me she loved me. I know that not every family is so lucky. And now as I move through the first milestones without her - her birthday, Christmas, the new year - I’m reminded that for someone else with dementia, these milestone moments will be their last.”

Right now, nearly half a million Australians are living with dementia, and without breakthroughs in treatment or prevention, that number is expected to double in the next 30 years. Research is the key to changing that.

❤️ Donate today ❤️
www.donate.centenary.org.au

26/11/2025

🕊️ Remembering Aidan and all of those who have died from sudden cardiac death 🕊️

On a quiet morning in May 2018, 22-year-old Aidan never made it to university. His heart stopped suddenly, without warning. Later, his family learned he had Vascular Ehlers-Danlos Syndrome—a rare genetic condition not typically linked to sudden cardiac death. Aidan’s story is one of heartbreak, mystery and the urgent need for research.

He was a gentle soul who loved poetry, politics and the simple joys of life. In his memory, his family created the Walk for Life—an annual event to honour young lives lost too soon and support families navigating unimaginable grief.

Join us on Sunday 30 November at 10am in Centennial Park (pictured) for Walk for Life 2025. Let’s walk for Aidan and all of those who have died from sudden cardiac death. Let’s walk for answers. Let’s walk for hope. 💙

🔗 Register now: https://walkforlife.sydney/rsvpmaker/walk-for-life-2025/

20/11/2025

Centenary Institute researchers played a prominent role in this week’s Australian Biology of Ageing Conference 2025, sharing new insights into how Australians can live healthier, longer lives.

The national conference, hosted by the Australian Biology of Ageing Network, brought together leading scientists to explore the biology of ageing, at a time when around 4.4 million Australians are now aged 65 and over.

At the conference, Centenary’s Professor Jenny Gamble shared new work on vascular leakage and Alzheimer’s disease, while Professor Devanshi Seth outlined advances in ageing biology and geriatric pharmacology. Dr Isabelle Alldritt presented findings showing how structured exercise can boost muscle function in people with sarcopenia.

Conference convenor and Head of Centenary’s Centre for Healthy Ageing, Professor Andy Philp - also a senior researcher at UTS Sydney - said the event reinforced the importance of collaboration in tackling diseases associated with ageing and improving quality of life for older Australians.

Read more: https://www.centenary.org.au/news/centenary-researchers-share-insights-at-ageing-conference/

13/11/2025

Centenary’s Associate Professor Richard Bagnall and Yuchen Chang, PhD candidate at the University of Sydney and the Centenary Institute, have uncovered new genetic causes of inherited heart conditions, giving more families vital answers that can guide treatment and prevention.

Using the latest genomic analysis techniques, the researchers and their collaborators, found additional genetic diagnoses for 4% of participants in a national study, helping explain the cause of their heart disease and confirming a new gene, TBX20, linked to cardiomyopathy.

This breakthrough highlights the power of continually re-examining genomic data to improve diagnosis and care for people living with inherited heart conditions.

Read more: https://www.centenary.org.au/news/new-gene-discoveries-improve-diagnosis-of-inherited-heart-disease/

04/11/2025

The Centenary Institute shared the beauty of science with the wider community through its When Art Meets Science exhibition, featured at Government House Sydney during Sydney Open Day.

Thousands of visitors explored stunning imagery created by our scientists - from stem cells resembling blooming flowers to epithelial cells looking like deep space nebula.

The images offered a glimpse into the microscopic world where our researchers work to combat disease and improve lives.

Many of these captivating works were part of Centenary’s 2025 When Art Meets Science Image Prize competition, a celebration of the creativity and beauty found in scientific discovery.

Read more: https://www.centenary.org.au/news/centenary-exhibits-at-government-house/

Centenary Institute

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