20/12/2024
Hormone Levels In PCOS Women have significant difference in thyroid-stimulating hormone (TSH), prolactin, luteinizing hormone (LH), Follicle stimulating hormone (FSH), and testosterone level.
Jyoshna, D.P., Vijayasree, D., & Gayathri, D.C. Hormonal Profile in PCOD patients: A Case-Control Study at a Tertiary Care Center. Feb 2023
This case-control study was done at a tertiary care center among 100 subjects in the department of Biochemistry at Kurnool Medical College, Andhra Pradesh, from July 2022 to December 2022.
Group C includes 50 female controls or normal subjects. Group P includes 50 females diagnosed with PCOS. All subjects were aged above 18 years.
Hormonal levels between two groups of patients were assessed and compared.
Results : There is no significant difference in the mean age of patients in both groups. There is a significant difference in thyroid-stimulatinghormone (TSH), prolactin, luteinizinghormone (LH), Follicle stimulating hormone (FSH), and testosteronelevels between cases and controls.All these levels were more in cases compared to controls. LH/FSH ratio is also significantly more in cases compared to controls.The incidence of hirsutism is significantly more in cases compared to controls. Conclusion: We found that PCOS is associated with abnormal thyroid profile and reproductive hormones. This implies the significance of early correction of thyroid disorders in managing fertility issues associated with PCOS. All women with PCOS should have their thyroid function tests and hormonal tests monitored regularly.