01/03/2026
A major 2025 scientific review confirmed that Exercise is one of the most Powerful Evidence-based Treatments we have for Depression and Anxiety.
Published in the British Journal of Sports Medicine, the umbrella review analysed 81 meta-analyses, 1,079 randomized controlled trials, and nearly 80,000 participants—making it one of the most comprehensive examinations of exercise and mental health to date.
The findings show that structured physical activity significantly reduces symptoms of depression and anxiety in both clinical and non-clinical populations. Group-based and supervised exercise produced stronger antidepressant effects than exercising alone, highlighting the role of social connection and nervous system regulation. For anxiety, shorter and lower-intensity sessions were often as effective—or more effective—than long, intense workouts.
The authors concluded that exercise affects the same core mood-regulation systems targeted by conventional treatments, while also improving overall physical health and long-term resilience. Biologically, movement supports mitochondrial function, reduces inflammation, enhances neuroplasticity, and improves dopamine, serotonin, and stress hormone regulation.
Overall, the research reinforces that mental health is deeply connected to the body—and that movement, especially in connection with others, is a powerful therapeutic intervention.
Credit to .e.west
