Dr. Sandeep Gupta

18/02/2026

There are few topics as layered and deeply felt as hormonal balance. For many, the journey through symptoms, questions, and possibilities can feel heavy, confusing, or unresolved. Rather than rushing to simple explanations, a root-cause perspective invites us to look with patience and curiosity — observing patterns, asking thoughtful questions, and contextualising individual experience within the broader landscape of lifestyle, physiology, and time.

Bio-identical hormone treatment is one such area where a nuanced lens can be helpful. Looking at how hormonal therapies are understood over the long term encourages a reflective approach — one that honours both scientific inquiry and the lived experience of people navigating these choices.

If this resonates, you’re welcome to explore this conversation further and consider how these perspectives intersect with your own health narrative.

Read more here:
🔗 https://www.lotusholisticmedicine.com.au/blog/bio-identical-hormone-treatment-long-term-effects/

17/02/2026

Great info !

Glycine works for sleep but doesn't work like a typical "sleep supplement." It works like a thermostat.

When you take 3g of glycine before bed, it crosses the blood-brain barrier and binds to NMDA receptors in the suprachiasmatic nucleus, the brain's master circadian clock. This activates the medial preoptic area, which triggers peripheral vasodilation: blood flow increases to your hands and feet, heat radiates out through the skin, and your core body temperature drops. That temperature drop is the same signal your body produces naturally before sleep onset. Glycine just makes it happen more reliably.

This was mapped at Stanford by Kawai and colleagues. When they ablated the SCN in animal models, glycine's sleep-promoting and hypothermic effects disappeared entirely, confirming this is the target, not a downstream side effect. In human trials, 3g before bed reduced sleep-onset latency and next-day fatigue in volunteers with sleep complaints.

Polysomnographic data showed improved subjective sleep quality correlated with the temperature shift. The practical detail nobody mentions: glycine is one of the cheapest amino acids on the market. A 3g dose costs roughly nine cents. It has no sedative hangover because it isn't a sedative. It works through the same thermoregulatory cascade that a hot bath before bed exploits, peripheral vasodilation leading to core cooling, except it initiates it centrally rather than peripherally.

*None of this means glycine replaces sleep hygiene or addresses underlying sleep disorders. .

Kawai et al., Neuropsychopharmacology, 2015
Bannai et al., Frontiers in Neurology, 2012
Yamadera et al., Sleep and Biological Rhythms, 2007

16/02/2026

Mycotoxins can accumulate quietly without smell yet still affect liver function, methylation, and mitochondrial health. For some, this may trigger subtle autoimmune reactions or brain inflammation, showing up as fatigue, brain fog, or behavioral changes.

Join the second cohort of the Mold Illness Mastery Course to explore these insights in depth with Dr. Amy Derksen and Dr. Sandeep Gupta.

https://lotusinstitutehh.com/mold-illness-mastery/

12/02/2026

Wellness isn’t simply about adding supplements into your routine—it’s about supporting the body’s natural ability to eliminate and restore balance. Certain agents, like bentonite, and thoughtfully selected nutrients can play a role, but individual response always matters. Dr. Amy Derksen, the co-instructor for Mold Illness Mastery Course explains these concepts in this video.

Benfotiamine, a fat-soluble B1, is one example. It may support mitochondrial function, helping the body maintain energy and cellular processes under stress, while also assisting in binding certain mycotoxins and preventing mold from creating mycotoxins.

Last few hours to join the first cohort of the Mold Illness Mastery Course to explore these insights in depth with Dr. Amy and myself.

https://lotusinstitutehh.com/mold-illness-mastery/

07/02/2026

Excited !

26/01/2026

Our health does not exist in isolation.

Every day, the body is quietly responding—to the air we breathe, the spaces we inhabit, the food we consume, and the rhythms of daily life. Environmental and nutritional medicine invite us to look at these influences together, not as separate domains, but as interconnected parts of a larger story.

This perspective isn’t about blame or quick answers. It’s about curiosity. About noticing patterns over time. About recognising that persistent health challenges often have layers—shaped by both internal processes and external exposures.

Nutritional medicine considers how the body utilises nutrients as part of its ongoing adaptation to life. Environmental medicine broadens that lens, acknowledging that our surroundings also participate in this dialogue. When these approaches are viewed side by side, they offer a more complete context—one that respects the complexity of the human system.

At Lotus Holistic Medicine, this integrated way of thinking reflects a commitment to root-cause exploration and collaborative care. It creates space for thoughtful investigation, without urgency or assumptions—only careful listening and respect for each individual’s experience.

Health, in this sense, becomes less about isolated symptoms and more about understanding the whole terrain in which the body is living.

Read more: https://www.lotusholisticmedicine.com.au/blog/combine-environmental-and-nutritional-medicine/

22/01/2026

Longevity is rarely shaped by dramatic changes. More often, it reflects the quiet consistency of daily rhythms—how we hydrate, move, rest, nourish ourselves, and respond to stress over time. This piece reflects on the small, steady habits that support wellbeing across the lifespan, especially within the relaxed yet active lifestyle of the Sunshine Coast.

Rather than striving for perfection, it invites a gentler view of health—one grounded in sustainability, awareness, and respect for the body’s natural pace.

Read the full blog here:
https://www.lotusholisticmedicine.com.au/blog/daily-habits-to-extend-healthy-lifespan/

20/01/2026

Great info.

This benefit applies to both green and black tea, though green tea may have a slight advantage. Part of this protection may be a lower risk of dying of pneumonia. Five randomized, controlled trials have shown that study participants randomized to green tea are about a third less likely to come down with the flu.

Within just one hour of drinking a single cup (200 mL) of green tea, we can significantly cut down on the rate of DNA damage in our cells. This is because green tea significantly boosts the activity of a DNA repair enzyme in our body that can fix DNA damage. And within a month, drinking two small daily cups (400 mL) of green tea can improve DNA resistance to free radical damage in the first place, indicating that green tea has significant genoprotective––that is, DNA-protecting––effects.

Watch "How Not to Age – Live Presentation" at https://see.nf/47dqCnJ to learn more.
Unlike most antiviral drugs, green tea appears to work by boosting the immune system to combat diseases such as ge***al warts (caused by HPV) and the flu (caused by the influenza virus).

See the video "Benefits of Green Tea for Boosting Antiviral Immune Function" at https://see.nf/3v8xcxH to learn more.

PMIDs: 31216091, 19625686, 34209247, 24585444, 20807462, 21338496, 17914132, 25807215, 12719524

19/01/2026

In the warmth of the Sunshine Coast summer, many people notice a quiet kind of tiredness that doesn’t always make sense. When longer days, heat, shifts in routine, and subtle changes in how the body functions come together, energy can feel unexpectedly fragile. This perspective gently explores what might be influencing that experience—not as a label, but as a conversation with your own rhythms and patterns.

We invite you to read with curiosity and compassion, recognising that fatigue often has many layers. A whole-body view can create space for understanding what your energy may be communicating.

Read more here: https://www.lotusholisticmedicine.com.au/blog/what-causes-summer-fatigue/

15/01/2026

Your difficulties and hurdles are not a distraction from your path.

They are your path.

14/01/2026

In the quiet of a clinical sanctuary, we often find that health is not a single destination, but a nuanced conversation between the body and the life we lead.

For many, the path to wellness has felt hurried or fragmented—a collection of symptoms addressed in isolation. An Integrative Health Practitioner approaches care differently, acting as a dedicated investigator of the "why." Our role is to sit with you in the complexity, bridging the gap between clinical science and the practicalities of your daily lifestyle.

At the heart of our practice is the philosophy of The Root Cause. We view symptoms not as errors to be silenced, but as meaningful signals from your internal systems. By looking deeply into the interconnected layers of your biology—from gut health and hormonal balance to the quiet influence of the nervous system—we move toward a more complete understanding of your unique health landscape.

This is a collaborative journey of investigation and nurturing, designed to offer clarity where there has been frustration. We invite you to read our latest reflection on how this integrative model serves as a foundation for long-term vitality.

https://www.lotusholisticmedicine.com.au/blog/role-of-integrative-health-practitioner/