22/11/2025
🧪 N-Acetylcysteine (NAC) & Contrast-Induced Acute Kidney Injury (CI-AKI) 🩺
If you or a loved one requires a scan using contrast dye, this is important to know. 💡
Contrast-Induced Acute Kidney Injury (CI-AKI) is a possible complication of imaging procedures that use contrast dye (such as CT scans, angiograms or MRIs). For some individuals, contrast can be highly nephrotoxic, so supporting the kidneys before and after the procedure is crucial.
One well-researched strategy? N-Acetylcysteine (NAC), thanks to its antioxidant and kidney-protective effects. 🌿
🚩 Who Is at Higher Risk of CI-AKI?
Individuals with any of the following risk factors should be monitored closely:
• Pre-existing kidney disease (eGFR < 60 mL/min)
• Diabetes mellitus
• Dehydration
• Heart failure
• High contrast volume or repeated doses
💚 How NAC Supports Kidney Protection
N-Acetylcysteine may help reduce the risk of CI-AKI by:
✅ Reducing oxidative stress – lowers reactive oxygen species that can damage kidney cells
✅ Improving renal blood flow & oxygenation
✅ Reducing inflammation – helps minimise contrast-induced tissue damage
✅ Improving serum creatinine levels in some studies
✅ Reducing apoptosis & fibrosis
✅ Protecting renal tubules from injury
If you are scheduled for a contrast scan, speak with your healthcare practitioner first about risk reduction and whether NAC may be appropriate for you. 🩺✨
Can N-acetyl Cysteine Prevent Kidney Damage? N-acetylcysteine or NAC is a nutritional supplement that comes from the amino acid cysteine