17/12/2025
In disappointing news, the Phase 3 Sanofi trial of tolebrutinib in people living with primary progressive multiple sclerosis (PPMS) has not been successful. The company also announced that the U.S. Food and Drug Administration decision on tolebrutinib for non-relapsing secondary progressive MS (SPMS), which was expected before the end of 2025, has been delayed and is now expected by March 2026.