Type1Screen

23/12/2025

Wishing all our Type1Screen friends and families a relaxing, safe and joyful festive season.

20/12/2025

Introducing today's Type1Screen trooper, Mehdi!

Mehdi is a brave 5 year old who participated in Type1Screen because his 10 year old big brother was recently diagnosed with .

We're pleased to report that big brother is doing well and stoicly says, "...it could be worse". Wow. What a superstar! His diabetes educators are amazing and they have helped the family a lot. His mum reports he is not missing out on anything and still having a blast 💥

Sounds like Mehdi is from a family of troopers!

Thank you so much Mehdi, mum and family for supporting Type1Screen, and raising awareness.

💙

17/12/2025

New evidence shows that transplantation of islet cells (the cells that make ) may offer more than stable glucose levels for people with .

A systematic review of 25 studies (1,373 participants) found that both alone and islet-after-kidney transplantation not only helped reduce severe and improve day-to-day levels — the procedure may also protect long-term vascular health.

🔹 Microvascular benefits: Many studies reported stabilisation or even improvement in eye, kidney, and nerve-related complications.
🔹 Kidney outcomes: Long-term kidney function often remained stable after transplant.
🔹 Macrovascular signs: Although data are limited, some studies showed better markers of cardiovascular health, suggesting possible long-term heart-health benefits.

Overall, the review reinforces that for carefully selected adults with , islet transplantation can support both glucose stability and broader vascular health, with especially strong evidence for microvascular protection.

The article is: Gariani K, Peloso A, Haidar F, Kumar R, Wassmer C-H, Morabito M, Krause N, Compagnon P, Berishvili E and Berney T (2025) Impact of Islet Transplantation on Type 1 Diabetes-Related Complication: A Systematic Review. Transpl. Int. 38:15091. https://doi.org/10.3389/ti.2025.15091

14/12/2025

🧪 Good news on the "forever chemicals" front!

A Finnish study investigated whether (per- and polyfluoroalkyl substances), persistent or "forever" chemicals found in non-stick pans, waterproof clothing, and firefighting foam, might trigger in children.

🔍 What they did: Researchers measured PFAS levels in samples from 6-month-old babies, then tracked whether they developed or not over time. They compared two groups born in different decades (1996-2004 vs 2010-2019).

📊 Key findings: No link was found between early PFAS exposure and development

PFAS levels in children have dropped dramatically—from 15 ng/mL to 5 ng/mL between the two time periods measured (a 67% decrease!) Children who later developed T1D actually had slightly lower PFAS exposure than those who didn't, though the difference wasn't significant.

💡 The takeaway: While we know genes play a major role in T1D and environmental factors likely contribute too, this study suggests PFAS exposure in infancy is unlikely to be a culprit. Plus, PFAS levels in children are declining; reassuring evidence environmental regulations and policies are working.

With 9 million people worldwide living with T1D, understanding what does and doesn't cause it remains crucial research. That's why Australia's ENDIA Study is critical to answering this question!

ENDIA

11/12/2025

Thanks to Breakthrough T1D Australia for helping to raise awareness and support research. to progressing care, prevention, delay and eventually a cure 🤞🏻

11/12/2025

11/12/2025

Could early screening change how children experience type 1 diabetes diagnosis?

A new and was presented at the Annual Meeting of the British Society for Paediatric Endocrinology and Diabetes in the UK last month.

Researchers found that screening for islet autoantibodies (markers used to identify early-stage ) leads to significantly better outcomes at .

Looking at the data of more than 29,000 children, those who were screened before diagnosis had:
• 35% lower levels
• 24% lower risk of diabetic ketoacidosis ( )
• Reduced hospital admissions at diagnosis

These findings highlight the real-world benefits of proactive screening—giving families earlier support, safer diagnoses, and better long-term health outcomes. Screening also helps identify young people who may benefit from new and emerging aiming to delay and prevent the progression of

💙

08/12/2025

What if the presentation of type 1 diabetes wasn’t the same for every child?

A new study from Sweden’s national Better Diabetes Diagnosis project found that a small number about 6% (169/2,753) of children newly diagnosed with had no early markers ( ). Antibodies are a hallmark usually linked to diagnosis of autoimmune diabetes.

These children were more often male, had higher levels at diagnosis, and were more likely to have a family history of . Interestingly, their risk of diabetic ketoacidosis ( ) was *lower* than those with autoantibodies.

These findings suggest there may be distinct and different pathways leading to , revealing important clues about its underlying biology and how to improve identification and care in the future.

Given this finding in a minority of children, it's important to know the four T of type 1 diabetes: Tired, Thirsty, Thinner and Toileting more than usual

05/12/2025

Have you heard of "Teplizumab"? This is an immune therapy shown to delay the onset of clinical or symptomatic in young people. It targets immune cells that attack insulin-producing cells in the .

"Stage 2 type 1 diabetes" is an early phase in the process of development. The immune attack has begun, there is (abnormal blood glucose levels), but have not yet appeared.

The PETITE-T1D trial is the first study to test in children under 8 years of age with stage 2 . Over a period of two years, 23 children received a 14-day course of treatment.

Results at **one year** showed teplizumab was generally safe and well tolerated. Three of the 23 children discontinued treatment, with mild to moderate side effects similar to those seen in older age groups (anemia, elevated liver enzymes, and a rash). No new safety issues were identified.

At the time of reporting, 90% of participants had not progressed to stage 3 (symptomatic / clinical) .

These findings suggest teplizumab could help protect even the youngest at-risk children, delaying the onset of clinical type 1 diabetes. Further monitoring of these children continues.

Read more online at: https://rdcu.be/eQeLm

02/12/2025

✨ Getting Ready for the Christmas Holidays with Type 1 Diabetes ✨

The festive season can be full of joy, treats, travel, and a few extra curveballs — so a little planning can make things feel smoother and less stressful. Here are a few gentle reminders to help you feel prepared and confident heading into the holidays:

🎄 Stock up early
Pharmacies and clinics have reduced hours over and New Year, so it’s worth checking your supplies now. Think sensors, test strips, pump consumables, ketone strips, pen needles, and spares for everything you rely on.

🎄 Double-check your insulin
Make sure you’ve got enough fast-acting and long-acting insulin to cover the full break (plus a buffer, just in case). If you’re travelling, pack insulin in your carry-on and keep a cool bag handy.

🎄 Plan for festive food
Christmas meals can be rich, carb-heavy, and sometimes unpredictable. You don’t have to skip the things you love — just keep an eye on portions, think about timing of insulin, and check glucose a bit more often. Slow down, enjoy the food, and listen to your body.

🎄 Routine changes happen
Late nights, sleep-ins, extra activity (or none at all) can all shift glucose patterns. If numbers wobble, it’s not you doing anything wrong — it’s just life. Adjust as you need and give yourself a break.

🎄 Travel safely
If you’re heading away, pack a “T1D backup kit” with spares, hypo treatments, and a copy of your prescriptions. Keep things where you can reach them quickly.

🎄 Touch base with your care team
If you think you’ll need scripts, advice, or a check-in, book now before clinics close or staff go on leave.

✨ Most importantly: be kind to yourself.
The holidays can feel big in many ways. You deserve to enjoy this season with confidence, comfort, and the things (and people!) you care about.

Wishing everyone a calm, well-supported, and joy-filled Christmas. 💙

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