Type1Screen

Type1Screen offers Australian & New Zealand residents screening for the early detection of type 1 diabetes. Type1Screen is proudly supported by JDRF Australia.

This involves a blood test at your nearest pathology centre. Early detection can prevent serious illness & improve long term prognosis. Australian and New Zealand residents, who have a family member living with Type 1 Diabetes (T1D), are encouraged to find out more about Type1Screen. A simple blood test is all it takes to find out if you, or your child, at are increased risk of developing the condition. If you have a family history of T1D, when compared to the rest of the population, your risk of developing the condition is greater. Although there is currently no cure, early detection of T1D before symptoms present helps to prevent serious illness and provides options for intervention and prevention trials that may prevent or delay the onset of T1D.

17/11/2025

A and evaluated the efficacy of low-dose to prevent and treat exercise induced for people living with

Trials of low dose glucagon versus alternative therapies during controlled exercise were compared.

For individuals with , the study found low-dose glucagon reduces exercise-induced hypoglycaemia and time below range.

Making exercise more accessible for all individuals with will ultimately improve quality of life and help reduce diabetes-related complications.

Read more at: https://doi.org/10.2337/dc25-0702

13/11/2025

November 14th is International Diabetes Day 💙

Over 500 million people worldwide are living with diabetes. It is likely we all know someone living with diabetes! Whether it's Type 1, Type 2, Type3c, gestational, LADA, MODY or other types of diabetes, this condition affects real people—our colleagues, friends, and family members—every single day.

This International Diabetes Day, let's break the stigma and build understanding. The theme this year is "Diabetes at Work".

People with diabetes are managing their condition 24/7, making countless decisions about activity, medications, and even career choices that most of us never have to think about.

Here's at least 3 ways you can make a difference:
✅ Learn the early warning signs (the four Ts of T1D): excessive Thirst, frequent Toileting, unexplained Tiredness, getting Thinner
✅ Support, don't judge—diabetes management is complex and everyone's journey is different
✅ Get checked—early detection can improve long term outcomes, prevent serious complications, and may identify those eligible for clinical trials

Let's create a world where everyone with diabetes has the support, resources, and understanding they deserve.

💙

11/11/2025

November is Diabetes Awareness Month 💙
Did you know that 1.9 million Australians are living with ? Many of us know someone in our family, our workplace, or our footy team .
This year's theme is "Diabetes at Work" – because managing diabetes shouldn't mean missing out on career opportunities or feeling unsupported at your job.
Whether it's understanding when a colleague needs to check their blood glucose levels, ensuring access to medication storage, or simply creating a workplace culture where people feel safe to speak up about their health needs – we all have a role to play.
If you're living with diabetes, know your rights at work. If you're an employer or colleague, take time to learn how you can help create a supportive environment.
Let's work together to break down barriers and build workplaces where everyone can thrive.

08/11/2025

Hi! I am Arlo.

I am 7 years old and I am very .
This is me my after I had my finger pricked to do the Type1Screen test. It was a bit ouchy, but I didn't cry.
I found the blood drops interesting actually. Just 5 drops. And it was done.

My mum and dad helped me do this because my big brother has . He was only 1 when he was diagnosed 😢

For more information or to register someone with a family member living with go to www.type1screen.org

Thanks for supporting
💙

05/11/2025

🔬 Truly exciting news! Eli Lilly and Company is launching two major clinical trials for —a daily pill that could help preserve insulin production in people with the early markers for development, or recently diagnosed with .

Early studies led by members of our team in Australia, and funded by showed baricitinib helped people newly diagnosed with :
✅ Produce more insulin naturally
✅ Maintain blood glucose in target range
✅ Need less exogenous

The new trials will test whether baricitinib can:
1️⃣ Delay T1D onset in people found to have the early markers ( or early-stage T1D)
2️⃣ Preserve beta cells in people newly diagnosed (the cells that make insulin in the pancreas).

This drug is already approved for other conditions, and researchers are hopeful it could extend the "honeymoon period" when the pancreas can make its own insulin.

Might you or your family member be eligible? If you have ANY family history of , and thought about screening for , there has never been more motivation to do so. Check out our website for more information or to register for screening at www.type1screen.org

These trials will be open for recruitment globally soon, for those aged 1-35 years. Learn more via https://atic.svi.edu.au/clinical-trials/clinical-trials/ and spread the word!

ATIC Breakthrough T1D

02/11/2025

I'm sure you all know this nursery rhyme so feel free to sing along!

There were three in the bed and the little one said... Oh hang on a minute.... Not roll over... "I got screened!"

Yes, Dustin, Reagan and Aurora all snuggled up to support each other with the Type1Screen test for the early markers of (called ).

After being diagnosed 22 years ago this year, their mum, wanted to do everything to protect her kids from this condition. Hopefully no islet autoantibodies will be detected.

By detecting antibodies early, this gives families a chance to prevent (a life threatening condition with very high blood glucose levels), smooth the transition to therapy, and become eligible for available (check out the Australasian T1D Immunotherapy Collaborative).

For more information, or to register just like Dustin, Reagan and Aurora, go online to www.type1screen.org

31/10/2025

This trial provides the most convincing reason for screening family members for the early markers of ( ). For more information, or to register for screening, check out our website at www.type1screen.org

30/10/2025

Teplizumab is the first treatment proven to delay for those found to have early-stage . It is now FDA approved in America and under review for TGA approval in Australia.

However, researchers have discovered that helps some people with early more effectively than others! The difference may come down to how a person’s immune system works or is "tuned".

In this study by Sassi et al reported in the "Journal of Clinical Investigation", those people who responded well had more active immune cells (called T cells, NK/CD8⁺) that help control . In those who didn’t respond as well, other immune cells ( ) that drive inflammation were more dominant.

By analysing thousands of individual cells, the team identified a small group of 26 in the blood that can predict who is most likely to benefit from teplizumab, with high accuracy!

This research brings us a big step closer to personalised treatment and prevention for T1D. 🌟

To access Teplizumab, and other emerging therapies and to delay the need for therapy, individuals must be identified to be in early-stage before any symptoms develop. If you have a family history of , and want to determine your or your child's risk, check out our website www.type1screen.org for more information or to register.

Read more about the research in this open access article here: https://doi.org/10.1172/JCI176403

27/10/2025

💔 The Cost of Type 1 Diabetes Complications 💊

A major study in followed over 10,000 people living with and found that serious like kidney failure, heart disease, and severe low ( ) or high blood sugar ( ) can have a huge personal impact over time.

⚠️ Kidney transplants and end-stage caused the biggest disruptions, often requiring ongoing care and affecting quality of life. Even common issues like nerve damage and blood sugar emergencies can lead to repeat hospital visits and long recovery times.

👨‍👩‍👧‍👦 These complications don’t just affect the person with —they impact families, carers, workplaces, health care and communities. The emotional, physical, and financial toll is real.

🧠 Why it matters: These results show just how personally and financially costly T1D complications can be, especially if not identified and prevented early. Investing in better care and prevention could help people live healthier lives and reduce long-term personal and economic costs.

💡 This study is a powerful reminder of why early identification, support, access to care, and strong strategies matter—not just for saving costs, but for protecting lives.

Read more at https://doi.org/10.1016/j.diabres.2025.112329

22/10/2025

A groundbreaking early-phase has tested , a new stem cell–derived islet cell therapy, for people with .

✨ What’s zimislecel?
It’s a lab developed, donor-derived islet cell infusion designed to restore the body’s ability to produce

🔬 What did the study find?
Published in the prestigious New England Journal of Medicine (NEJM), 14 participants had no insulin production before treatment. After zimislecel, all showed restored islet function (cells which produce insulin in the ).

✅ 100% of participants avoided severe

✅ 83% achieved insulin independence after 1 year - wow

📉 They also spent over 70% of time in the healthy glucose range

Side effects included neutropenia (abnormally low level of , a type of white blood cell that helps fight infections).

💡 Why it matters:
This small but promising study suggests that cell-based therapies could one day reduce or even eliminate the need for insulin in some people with .

⚠️ Still early days—more research is needed. But it’s another step forward.

The paper is online: https://doi.org/10.1056/nejmoa2506549
or read the media release at: https://news.vrtx.com/news-releases/news-release-details/vertex-presents-positive-data-zimislecel-type-1-diabetes

19/10/2025

⚠️ Heavy metals & management

A study of Egyptian living with found:
🔹 82% had elevated lead levels
🔹 53% had elevated cadmium levels
🔹 Children with poorer glucose control (higher ) had much higher lead concentrations

Hair samples were analysed for potentially toxic elements (PTE) concentrations. Clinical and environmental data, including dietary habits and parental smoking, were collected.

🐟 Mercury was linked to fish intake, and cadmium to parental smoking 🚬— but neither was tied to HbA1c.

💡 Importantly: This study looked at glycemic control, not the cause of T1D. Findings suggest heavy metal exposure may make it harder for children with T1D to manage their blood glucose.

The article is accessible online at https://rdcu.be/eJfGu

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