25/09/2025
Where do I start?
Overnight Donald Trump and his unqualified Secretary of Health and Human Services announced that there was a causal link between paracetamol use in pregnancy and the development of autism. They announced that the medication would now be labelled to warn of this ‘risk’ and that guidance will be updated to discourage women from taking paracetamol in pregnancy.
The problem is that the ‘evidence’ suggesting a tenuous link is riddled with confounders, whereas the most stringent studies which account for familial confounding show that no such link exists.
In April 2024, a landmark study was published in JAMA which set out to address the question: does paracetamol use in pregnancy increase the risk of neurodevelopmental disorders in children?
The study was a nationwide cohort study with sibling control analysis, which included a population-based sample of 2,480,797 children born in 1995 to 2019 in Sweden, with follow-up through December 31, 2021.
That’s a 24 year cohort study, with the use of paracetamol during pregnancy prospectively recorded from antenatal and prescription records.
In total, 185,909 children (7.49%) were exposed to paracetamol during pregnancy. To address unobserved confounders that may skew the data, matched full sibling pairs were analysed.
Sibling control analyses found that there was no evidence that paracetamol use during pregnancy was associated with autism, ADHD or intellectual disability. Furthermore there was no evidence that increasing doses of paracetamol resulted in a higher risk of autism compared to those who had taken no paracetamol at all.
This nationwide cohort study has addressed important confounders that other studies have not addressed. It makes a compelling and evidence based conclusion: Paracetamol use does not cause autism, ADHD or intellectual disability.
I never once took paracetamol in my pregnancy with Mariam. She’s still autistic and I love every single inch of her.
Trump and his anti-vax Secretary of Disease continue to cause absolute chaos with their ignorance of science and evidence based medicine.
Because you know what is harmful to babies?
Untreated fevers in pregnant women.
Sustained fever of greater than 38.9 degrees for at least 24 hours has been shown to be associated with an increased risk of miscarriage, an increased risk of malformations including neural tube defects like spina bifida, and an increased risk of stillbirth in later pregnancy.
Paracetamol is a Category A medication which has a wide body of data which has demonstrated it is safe to use in pregnancy. It is the recommended analgesia in pregnancy due to the potential side effects of non steroidal anti-inflammatories.
Please do not listen to those issuing warnings about a medication that they cannot even pronounce.
And shame on this ignorant administration for continuing to demonise autistic people like my daughter as if they are some preventable mistake.
- Sara
📸 my beautiful brown eyed girl who is imperfectly perfect like all of us, doesn’t need ‘fixing’ and is the love of my life ❤️
Link to JAMA study https://jamanetwork.com/journals/jama/fullarticle/2817406