Murdoch Children's Research Institute - MCRI

Murdoch Children's Research Institute - MCRI Murdoch Children’s Research Institute is dedicated to making discoveries to prevent and treat common and rare childhood conditions.

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Murdoch Children's Research Institute (MCRI) is Australia's largest child health research institute and is ranked among the top three globally for research quality and impact. Our team of 1,800+ researchers works across over 150 common and rare diseases and conditions affecting children and adolescents. From allergies and asthma, diabetes and mental health issues to cancer and rare genetic disorders, we are relentless in our pursuit to transform child health through research and give all children the opportunity to live a healthy and fulfilled life. Our story began in 1986, when world-leading philanthropist Dame Elisabeth Murdoch and genetics pioneer Professor David Danks imagined a better future for our children and established the original Murdoch Institute for Research in Birth Defects. Since then, MCRI has grown from a genetics research institute to a global leader in child health. Our work also goes beyond research. MCRI is one of the only research institutes in Australia to offer genetic testing via our subsidiary, the Victorian Clinic of Genetic Services (VCGS), to find answers for families of children with previously undiagnosed conditions. Operating in a unique model with The Royal Children's Hospital and the University of Melbourne, MCRI is part of a great circle of healthcare and discovery – helping transform child health from the laboratories to clinics and out into communities.

Peanut allergy rates are dropping in the US. Early introduction may be the key 🔑New research shows a significant decline...
11/11/2025

Peanut allergy rates are dropping in the US. Early introduction may be the key 🔑

New research shows a significant decline in peanut allergies, a decade after guidelines encouraged parents to introduce peanuts and other allergens in the first year of life.

MCRI’s Associate Professor Rachel Peters and Associate Professor Jennifer Koplin unpacked the findings in The Conversation Australia + NZ and explored how Australian food allergy research continues to evolve.

Read more 👇

National Allergy Council Allergy & Anaphylaxis Australia

MCRI's A/Prof Rachel Peters & A/Prof Jennifer Koplin co-authored a piece in The Conversation, unpacking a US study and discussing how food allergy research in Australia continues to evolve.

Are you, or your teenager, battling hay fever this spring? Join a short trial to help manage symptoms once and for all a...
11/11/2025

Are you, or your teenager, battling hay fever this spring?

Join a short trial to help manage symptoms once and for all and earn up to $150 for contributing to research. It’s easy to take part:

✅ Three short video calls
✅ Three easy questionnaires
✅ Follow the education resources provided
✅ Use your daily nasal spray for six weeks

Find out about the National Allergy Centre of Excellence trial. Register today 👉 https://redcap.mcri.edu.au/surveys/?s=M9RE8TED87TNAME4

“It is...important to monitor heart rate and blood pressure while on treatment and exclude cardiac symptoms or signs, su...
09/11/2025

“It is...important to monitor heart rate and blood pressure while on treatment and exclude cardiac symptoms or signs, such as a murmur, before starting medication."

MCRI's A/Prof Daryl Efron spoke to the Herald Sun about the importance of heart health for young people taking stimulant-based medication for ADHD.

A new MCRI study found that the long-term effects of these stimulants were not well understood and recommended monitoring height, weight, heart rate and blood pressure to provide a better picture of overall health and progress.

Read the full story, also featuring MCRI's Dr Nadia Coscini 🗞️👇

US childhood food allergies are declining following changes in infant feeding advice, according to new research publishe...
03/11/2025

US childhood food allergies are declining following changes in infant feeding advice, according to new research published in American Academy of Pediatrics. There are signs Australia is on a similar path.

MCRI and National Allergy Centre of Excellence experts Associate Professor Rachel Peters and Professor Kirsten Perrett spoke with The Age about Australian guidelines for introducing common allergens, and our research into better treatment and prevention options for families.

Read more 👇

National Allergy Council Allergy & Anaphylaxis Australia

Australia has one of the highest rates of infant food allergies in the world. But new research from the US is producing promising results.

Almost a third of young people in Australia use vapes, with rates substantially increasing with age, according to a new ...
02/11/2025

Almost a third of young people in Australia use vapes, with rates substantially increasing with age, according to a new study.

The research, led by Murdoch Children's Research Institute, found 76 per cent of 21-year-olds have ever vaped. The highest prevalence was among 20-year-olds with 29.5 per cent va**ng at least monthly and 17 per cent va**ng weekly. Fewer young people smoked ci******es, yet 5 per cent of 20-year-olds were daily smokers.

MCRI Professor Susan Sawyer said that while the long-term damage of smoking was clear, va**ng was a toxicological experiment as the long-term damage was unknown.

"Preventing the use of all ni****ne products during this critical developmental period is urgently needed to avert the known and potential harms from va**ng and smoking," she said.

"These high rates of va**ng vindicate policies to regulate access to smoking and va**ng. Yet targeted marketing to young people continues, as well as poor enforcement of regulations banning the retail sale of ni****ne vapes to minors."

Read more in The Guardian 👉 https://www.theguardian.com/australia-news/live/2025/oct/22/australia-news-live-weather-nsw-qld-heat-record-melbourne-destructive-wind-rex-airlines-bid-albanese-washington-sussan-ley-labor-coalition-ntwnfb?CMP=share_btn_url&page=with%3Ablock-68f861328f082fc3b1776542 -68f861328f082fc3b1776542

**ng Cancer Council Victoria

“Born in distress and with an infection, multiple doctors told us they were unsure if she would survive the hospital tra...
31/10/2025

“Born in distress and with an infection, multiple doctors told us they were unsure if she would survive the hospital transfer, let alone surgery and then recovery.”

Courtney's daughter Lucy was diagnosed with congenital diaphragmatic hernia (CDH) at birth. This rare condition impacts development of the diaphragm and effects the lung, heart, gut and brain. Children with CDH have a 50/50 chance of survival, a fact that weighs heavily on young patients and their families.

While Lucy has hit her milestones and continues to thrive, children with rare or painful conditions like CDH face a unique set of physical and psychological challenges. We put Lucy's story in the spotlight as part of Mental Health Month to encourage others to share their stories and speak up about the importance of children's mental wellbeing in the face of chronic health conditions.

Recent research from Murdoch Children's Research Institute (MCRI) has shown work needs to be done to improve the care of CDH children after they leave hospital. While immediate, acute care remains strong, ongoing management of mental health and behavioural concerns can be patchy.

MCRI studies like Generation Victoria - GenV also track the mental health of children over a lifetime and provide valuable answers about the wellbeing of children with rare diseases like CDH as well as the wider community.

Read more about Lucy's story 👉 https://direc.to/nEBo

CDH Australia

If you or someone you know needs support, you can contact️:
Kids Helpline: 1800 55 1800
headspace : 1800 650 890
Lifeline: 13 11 14
Beyond Blue: 1300 22 4636
Butterfly Foundation: 1800 334 673

Children at the heart ❤️News Corp's VWeekend magazine cover and four page inside coverage explored Dame Elizabeth Murdoc...
27/10/2025

Children at the heart ❤️

News Corp's VWeekend magazine cover and four page inside coverage explored Dame Elizabeth Murdoch's legacy and MCRI's pioneering work in the science of stem cell and genomic medicine, public health and infectious diseases.

James Thornton, who was born with half a heart, was the cover story. The rare condition known as hypoplastic left heart syndrome is caused when the structures on the left side of the heart don’t develop properly. With no cure, his family said MCRI’s stem cell scientists were the family’s glimmer of hope.

Read more about MCRI’s research excellence in saving and transforming children's lives, and donate today 👉 https://www.mcri.edu.au/support/donate

Herald Sun

23/10/2025

Cerebral palsy is the most common physical disability of childhood. Research shows that three out of four children with cerebral palsy experience pain, and most of that is chronic pain.

Until recently, chronic pain has been under-identified, poorly assessed, and inadequately managed for children and young people with cerebral palsy.

MCRI’s Dr Adrienne Harvey and her team aim to partner with people with lived experience of cerebral palsy to co-create an innovative chronic pain intervention for children aged five-to-12 years. Your donations could help develop this program and improve the lives of children with cerebral palsy and their families. Visit our bio link to donate or learn more 💙

MCRI has proudly become a member of the Victorian Aboriginal Health, Medical and Wellbeing Research Accord 🖤💛❤️Led by Vi...
20/10/2025

MCRI has proudly become a member of the Victorian Aboriginal Health, Medical and Wellbeing Research Accord 🖤💛❤️

Led by Victorian Aboriginal Community Controlled Health Organisation Inc, this Accord is a powerful step toward ethical, culturally safe research practices that respect Indigenous cultures, knowledges, and aspirations.

“MCRI is honoured to walk alongside Community in this journey. Joining the Accord isn’t just a matter of policy – it’s a promise to listen, to learn, and to ensure our work lifts up Aboriginal and Torres Strait Islander children and families.” – MCRI Director Professor Kathryn North AC.

Together, we’re building a future where research strengthens trust, respect, and outcomes for First Nations children and families. Read more 👇

MCRI joins the Victorian Aboriginal Health Research Accord, advancing ethical, culturally safe research. Read more.

Calling all Aussie teens (13-16) and their parents 🤳In December, Australia is set to roll out a world-first social media...
13/10/2025

Calling all Aussie teens (13-16) and their parents 🤳

In December, Australia is set to roll out a world-first social media ban for under-16s and researchers want to hear from you. The Connected Minds Study, by MCRI and Deakin University, is tracking how this major change affects young people’s screen time, sleep, mental health and wellbeing.

Your involvement could help inform future policies that support young people’s wellbeing, like the regulation of digital content and media literacy for parents and adolescents.

Visit here for more info or contact connected-minds@mcri.edu.au 👉 https://direc.to/nH_T

MCRI and Deakin University launch teen study on Australia’s social media ban, tracking phone use and wellbeing impacts. Read more.

13/10/2025

The best start to life 🤝 🥹
 
Always a pleasure to have Victorian Minister for Health Mary-Anne Thomas visit us, touring our newborn bloodspot screening (NBS) lab and learning about Biotinidase deficiency, the latest condition that’s been added to Victoria’s NBS program.
 
A wonderful reminder of the real impact our work has on families like Jessica and her seven-month-old baby Elijah – who had their newborn screen when Elijah was born – giving every child the best start to life.
 

Address

50 Flemington Road
Parkville, VIC
3052

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm

Telephone

+61383416200

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