26/12/2025
NO #1 face serum designed by Soul Infused uses the best frankincense available
A study published in 2009 in BMC Complementary and Alternative Medicine (PMC2664784) investigated the effects of frankincense (Boswellia sacra) essential oil on human bladder cancer cells. Researchers treated human bladder carcinoma cells (J82) and normal human urothelial cells (UROtsa) with increasing concentrations of frankincense oil and measured cell viability and structural changes. The study found that frankincense oil caused a dose-dependent death of bladder cancer cells, while normal bladder cells were significantly less affected at the same doses, indicating selective cytotoxicity rather than generalized toxicity.
Further molecular analysis showed that frankincense oil altered the expression of genes involved in cell-cycle arrest, growth inhibition, and apoptosis specifically in the cancer cells. Notably, the cancer cell death did not follow the classic DNA-fragmentation pattern of apoptosis, suggesting a distinct, non-canonical mechanism of tumor cell elimination. These findings demonstrated that frankincense essential oil can selectively disrupt bladder cancer cell survival pathways in vitro, providing a mechanistic basis for further preclinical investigation.e