07/11/2025
Repost from William Wallace, Ph.D.
How vitamins and minerals shape brain health
The brain depends on a steady supply of micronutrients to create energy, build new cells, and protect neurons from damage. Each nutrient plays a specific role in cognition, memory, and mood regulation.
1️⃣ B-vitamins (B1, B2, B3, B6, B12, Folic acid)
Power the brain’s metabolism and neurotransmitter synthesis. Vitamin B1 drives glucose use, B2 and B3 support mitochondrial energy and memory, while B6 and B12 regulate mood and myelination.
🟢 Example: Low B12 or folate can impair DNA repair in neurons and raise homocysteine, a marker linked to cognitive decline.
🟢 Example: B1 deficiency reduces ATP in neurons, causing brain fog and fatigue.
2️⃣ Antioxidant vitamins (C and E)
Defend neural membranes from oxidative stress and preserve communication between brain cells.
🟢 Example: Vitamin E integrates into lipid membranes to prevent peroxidation; vitamin C regenerates oxidized E and supports neurotransmitter synthesis.
3️⃣ Vitamin A and D
Guide brain cell growth and differentiation, influencing neurodevelopment and plasticity.
🟢 Example: Vitamin A regulates genes for synaptic plasticity; vitamin D receptors in the hippocampus affect learning and mood.
4️⃣ Omega-3 long-chain fatty acids (EPA and DHA)
Form structural components of neuronal membranes and the central nervous system.
🟢 Example: DHA supports synaptic signaling and myelin formation; low levels correlate with slower processing and mood disorders.
5️⃣ Essential minerals (Iron, Magnesium, Copper, Selenium, Iodine)
Sustain energy metabolism, antioxidant defense, and neural signaling.
🟢 Example: Iron carries oxygen to brain tissue; magnesium stabilizes neuronal firing and enhances learning.
🟢 Example: Selenium protects against neuronal death through glutathione peroxidase; iodine fuels thyroid hormones that regulate brain development.
Balanced micronutrient intake keeps the brain’s energy systems, neurotransmitters, and structural integrity running smoothly; supporting clarity, focus, and resilience across the lifespan.
📷 William Wallace, Ph.D.