45 and Up Study

12/05/2025

$4.5 million grant for new study!

We’re thrilled to announce that the Sax Institute, which manages the 45 and Up Study, has been awarded a $4.5 million grant to establish a new multigenerational study into mental health. This new study is called the 18 and Up Study, and it will build on the power of the 45 and Up Study so that we can better understand the mental health challenges faced by different generations. Read more about the announcement and stay tuned for more information over the coming months.

A $4.5 million grant from the National Health and Medical Research Council (NHMRC) has been awarded to establish one of the largest intergenerational cohort studies in the world focused on mental health and wellbeing. The 18 and Up Study was announced today as one of the 22 successful projects funde...

16/04/2025

🚨New research from the University of Sydney reveals that the number of Australians living with diabetes may be up to 35 per cent higher than previously estimated. The Australia-first research was powered by data from the 45 and Up Study. The findings have big implications for how Australia plans health services and prevention strategies for diabetes. Thank you to the hundreds of thousands of 45 and Up Study participants who make this research possible! Read more 👉 https://www.saxinstitute.org.au/news/diabetes-prevalence-in-australia-may-be-35-higher-than-estimated/

05/03/2025

New research using the 45 and Up Study has shed light on the benefits of a healthy lifestyle for women who experienced premature or early menopause. Data from 46,000 women showed that women with premature menopause (before the age of 40) had an increased risk of heart disease, compared to women who reached menopause at the average onset age (50 to 52). But that risk was offset by the heart-health benefits of a healthy lifestyle. This research was funded by a Heart Foundation 45 and Up Research Grant, which has supported numerous projects since 2020. Learn more:
https://www.saxinstitute.org.au/news/healthy-lifestyle-a-heart-saver-for-women-with-early-menopause/

30/01/2025

Thank you to the thousands of 45 and Up Study participants who took part in the Maintain Your Brain trial. Findings have just been published, showing that an online lifestyle coaching program significantly improved cognitive ability in older adults. Cognitive decline can lead to dementia, making improving cognition as you age key to prevention. This powerful evidence could make a difference to health of many Australians in the future. https://www.saxinstitute.org.au/news/cognition-in-older-adults-improved-in-clinical-trial-using-45-and-up-participants/

22/12/2024

19/12/2024

Thanks to your generous support, the 45 and Up Study has informed important research on cancer, diabetes and other pressing health issues this year. In 2024, research by prestigious institutions including the University of Sydney, The Garvan Institute, the Daffodil Centre and the University of Technology Sydney have generated global media attention and have helped inform decision making. Find out more about what the 45 and Up Study has told us this year… https://www.saxinstitute.org.au/news/what-the-45-and-up-study-told-us-in-2024/

24/10/2024

New research by The Daffodil Centre using data from the 45 and Up Study has revealed high out-of-pocket costs incurred by cancer patients in Australia.
Researchers looked at data from 45,000 participants in 45 and Up Study. They found that more than half of people diagnosed with cancer in the previous two years had annual out-of-pocket costs higher than $1000, and almost one in ten had costs over $10,000.
Learn more about the research here: https://www.saxinstitute.org.au/news/cancer-patients-hit-by-high-out-of-pocket-costs/