06/11/2025
This Cheat Sheet summarises current evidence and guidance for managing advanced and metastatic renal cell carcinoma (RCC).
Download this Cheat Sheet here:
https://uroweb.org/guidelines/renal-cell-carcinoma/related-content
It covers the role and timing of cytoreductive nephrectomy, indications for local therapy such as embolisation, stereotactic radiotherapy, and metastasectomy, as well as systemic treatment strategies including immune checkpoint inhibitors and tyrosine kinase inhibitors.
The focus is on patient selection, treatment sequencing, and balancing surgical and systemic approaches.
Data from major trials such as CARMENA and SURTIME inform current practice, while ongoing studies continue to refine long-term outcomes and optimal integration of immunotherapy. Based on the EAU Guidelines on RCC.