22/11/2025
https://zurl.co/NQz35 Pragmatic guidance details vasopressin’s bedside use in septic shock: earlier initiation (within six hours, at lower norepinephrine doses) is associated with better outcomes, fixed dosing up to 0.04 IU/min is safe, 0.06 IU/min is feasible with vigilance for digital ischaemia, central-line infusion is advised, and large trials showed no overall survival advantage, with possible renal benefit in select contexts.
