Journal of Applied Oral Science

Journal of Applied Oral Science Impact Factor (2024) : 2.6
Open-access, international journal. Science & Technology, Dentistry & Speech-Language Pathology and Audiology.

Published by Bauru School of Dentistry/University of São Paulo.

🎯Selective HDAC4 inhibition by SP1-PTD promotes odontoblast differentiation🔗https://doi.org/10.1590/1678-7757-2025-0447✍...
19/12/2025

🎯Selective HDAC4 inhibition by SP1-PTD promotes odontoblast differentiation

🔗https://doi.org/10.1590/1678-7757-2025-0447

✍️
Yeo-Kyeong SHIN
Jung-Sun MOON
Su-Kyeong SON
Bin-Na LEE
Chungoo PARK
Sun-Hun KIM
Young Chul LEE
Min-Seok KIM

🎯Modification of restorative glass ionomer cement with zinc oxide nanoparticles and calcium glycerophosphate micropartic...
16/12/2025

🎯Modification of restorative glass ionomer cement with zinc oxide nanoparticles and calcium glycerophosphate microparticles: in vitro assessment of mechanical properties and antimicrobial activity

🔗https://doi.org/10.1590/1678-7757-2025-0356

🎯Evaluation of the levels of Fractalkine (CX3CL1), TNF-α, and TGF-β in the gingival crevicular fluid/tissue of patients ...
12/12/2025

🎯Evaluation of the levels of Fractalkine (CX3CL1), TNF-α, and TGF-β in the gingival crevicular fluid/tissue of patients with gingival overgrowth: a cross-sectional observational study

🔗https://doi.org/10.1590/1678-7757-2025-0304

🎯Conditioned media from monocytes and macrophages significantly impact the proliferation, invasiveness, and gene express...
09/12/2025

🎯Conditioned media from monocytes and macrophages significantly impact the proliferation, invasiveness, and gene expression of SCC cells, underscoring the critical role of the tumor microenvironment in cancer progression.

🔗https://doi.org/10.1590/1678-7757-2025-0380

🎯In this study, it was observed that certain oral bacteria exhibit distinct characteristics in Kazakhstani adolescents w...
05/12/2025

🎯In this study, it was observed that certain oral bacteria exhibit distinct characteristics in Kazakhstani adolescents with and without dental caries. Specific species, such as Neisseria and Prevotella, demonstrate the adaptation of their metabolic strategies to thrive under acidic and stressful conditions. However, these metabolic changes consequently render the oral environment more vulnerable to dental caries. The findings underscore the importance of maintaining a delicate balance between the microbiota and metabolism to promote better dental health in young individuals.

🔗https://doi.org/10.1590/1678-7757-2025-0476

🎯This study showed that posterior composite restorations performed well with universal adhesive system, regardless of th...
28/11/2025

🎯This study showed that posterior composite restorations performed well with universal adhesive system, regardless of the adhesive strategy used. These results highlight the strong and reliable performance of universal adhesives in real clinical settings and provide valuable guidance for clinicians performing direct posterior restorations.

🔗https://doi.org/10.1590/1678-7757-2025-0402

💡In patients treated with OS, skeletal advancement resulted in greater increases in mandibular and corpus lengths, along...
27/11/2025

💡In patients treated with OS, skeletal advancement resulted in greater increases in mandibular and corpus lengths, along with forward positioning of the pogonion. Based on 3D soft tissue and cephalometric comparisons, the Herbst appliance seems to be a viable non-surgical alternative for young adults with moderate Class II malocclusion. Both treatment modalities also contributed to significant improvements in sagittal oropharyngeal airway length.

🔗https://doi.org/10.1590/1678-7757-2025-0310

🎯A randomized prospective clinical study evaluating the effectiveness of the Beautibond Xtreme adhesive system using dif...
17/11/2025

🎯A randomized prospective clinical study evaluating the effectiveness of the Beautibond Xtreme adhesive system using different bonding techniques in class I and II restorations: one-year results

CI: Class I cavities restored with the total acidetching technique
CII: Class II cavities restored with the total acidetching technique
TI: Class I cavities restored with the self-etching technique
TII: Class II cavities restored with the self-etching technique
TIII: Class I cavities restored with the selectetching technique
TIV: Class II cavities restored with the selectetching technique

🔗https://doi.org/10.1590/1678-7757-2025-0228








🎯Diabetes often compromises bone healing, making implants more likely to fail.In this study, the authors found that a lo...
12/11/2025

🎯Diabetes often compromises bone healing, making implants more likely to fail.
In this study, the authors found that a local injection of a molecule called 3S-HMGB1 improved bone growth and implant stability in diabetic mice.
The treatment restored bone-to-implant contact to near-healthy levels and enhanced tissue organization.
These results highlight 3S-HMGB1 as a promising strategy to counter early implant failure in diabetes.
Future work will explore ways to optimize delivery strategies and extend its benefits over the long term.

🔗http://dx.doi.org/10.1590/1678-7757-2025-0358

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Bauru, SP
17.012-901

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