Memory Medicine

Memory Medicine Approaching memory loss through cutting edge assessment and support.

Gut microbiome imbalance (dysbiosis) is increasingly linked to Alzheimer’s disease via the microbiota–gut–brain axis. Lo...
02/21/2026

Gut microbiome imbalance (dysbiosis) is increasingly linked to Alzheimer’s disease via the microbiota–gut–brain axis.

Loss of microbial diversity with age, diet, and environmental exposures can increase intestinal permeability and systemic inflammation, allowing microbial signals to negatively influence the brain.

We are starting to see that those with Alzheimer’s show distinct microbial patterns, fewer beneficial bacteria and more pro-inflammatory species - with changes correlating to disease severity and potentially preceding symptoms.

Fermented foods provide live microbes and bioactive compounds (including short-chain fatty acids) that help strengthen the gut barrier, regulate immune activity, and support anti-inflammatory, neuroprotective signaling.

What are your favourite fermented foods?

The connection between sugar and dementia isn’t new, but this study is one more piece of confirmation and takes it a ste...
02/19/2026

The connection between sugar and dementia isn’t new, but this study is one more piece of confirmation and takes it a step further - showing that genetics may make some people more sensitive to sugar’s effects on the brain.

Why is this? While we don't know all the mechanisms, high sugar intake can drive inflammation, insulin resistance, and weight gain - all factors that contribute to neurodegeneration.

What’s really important, is that participants were on average just 56 years old and followed for 10 years, highlighting a connection not just to dementia, but to early-onset dementia.

Of course, diet is only factor - but it's modifiable and the research is strong. It’s never too early to make mindful choices. And we’re here to help you do just that!

02/17/2026

The brain needs sleep to function at its best.

We’ve all experienced how hard it is to focus and concentrate after a poor night’s sleep. & if you pay close attention, you’ll notice that it’s harder to retain information and learn new things.

It’s not just a short term problem thought, the cumulative impact of poor sleep contributes to neurodegeneration

This is because during sleep the brain is busy performing essential maintenance, such as:

• Consolidating memories

• Clearing metabolic waste and toxins via the glymphatic system

• Repairing brain cells

• Organizing information and supporting neuroplasticity

We also see that levels of BDNF, a protective protein that supports brain health, are significantly lower in people with chronic sleep deprivation.

The takeaway? Intentionally plan to sleep at least 7 hours per night, most nights!

At Memory Medicine, our programs are based on the work of neurologist Dr. Dale Bredesen. We offer a comprehensive neuroc...
02/12/2026

At Memory Medicine, our programs are based on the work of neurologist Dr. Dale Bredesen. We offer a comprehensive neurocognitive assessment, as well as the PreCODE and ReCODE programs, designed to assess and support risk factors linked to dementia and Alzheimer’s. These evidence-based programs provide personalized strategies to support brain health, and we’re happy to answer any questions you may have—reach out to learn more!

NAD⁺ is an essential coenzyme found in every cell and plays a critical role in brain health. Levels naturally decline wi...
02/11/2026

NAD⁺ is an essential coenzyme found in every cell and plays a critical role in brain health.

Levels naturally decline with age and are further reduced by lifestyle factors such as poor diet, low physical activity, and impaired mitochondrial function.

In the brain, NAD⁺ supports energy production, neuronal repair, and protection against oxidative stress. It also plays a role in glucose regulation and insulin sensitivity, pathways increasingly recognized as modifiable risk factors for Alzheimer’s disease.

While research in humans is still emerging, growing evidence suggests NAD⁺ is involved in key processes that support long-term cognitive and brain health.

A large trial looked at almost 34,000 people aged 40+ with uncontrolled high blood pressure to see how lowering BP affec...
02/11/2026

A large trial looked at almost 34,000 people aged 40+ with uncontrolled high blood pressure to see how lowering BP affected dementia risk.

Over 4 years, trained community health providers helped one group lower their blood pressure to below 130/80 ... dropping systolic pressure by about 22 points.

That group had a 15% lower risk of all-cause dementia and 16% lower risk of cognitive decline compared with usual care.

The take away from this study is that managing blood pressure isn’t just good for your heart, it may help protect your brain too!

Read the whole study---> PMID: 40258956

02/09/2026

Vitamin D plays multiple roles in the brain, contributing to neuroprotection across the lifespan.

In contrast, low vitamin D levels have been associated with brain fog, reduced cognitive function, and an increased risk of dementia.

Because of this, testing your vitamin D levels is a practical, actionable step you can take to support long-term brain health.

Depending on your results, supplementation may help restore levels to a range that supports optimal brain function.

A long-term Japanese study followed 4,171 adults aged 40–69 for approximately 15 years to explore the relationship betwe...
02/07/2026

A long-term Japanese study followed 4,171 adults aged 40–69 for approximately 15 years to explore the relationship between diet and dementia risk.

Those with the highest intake of riboflavin (vitamin B₂) from food sources, rather than supplements, had up to a 49% lower risk of developing disabling dementia compared with those with the lowest intake.

This research shows an association rather than direct cause and effect, but it adds to growing evidence supporting that a whole foods, balanced diet including essential nutrients like vitamin B₂ is important for long-term cognitive health.

The link between blood sugar and cognitive health, especially neurodegenerative disease, is a big conversation, and this...
02/03/2026

The link between blood sugar and cognitive health, especially neurodegenerative disease, is a big conversation, and this study brings up some really interesting points.

1. The researchers found that the increased risk wasn’t due to brain shrinkage. Instead, it seems to come down to metabolic factors.

2. They also pinpointed a specific time: blood sugar spikes within about two hours after meals were linked to higher risk.

This is huge, because it gives us more insight into how the brain works, and what we can do to better support it.

Note: These findings were seen in people with a genetic tendency toward higher post-meal blood sugar, highlighting just how important bioindividuality is when it comes to prevention

Emerging research suggests that keeping our bones strong may benefit the brain as much as it protects against osteoporos...
02/02/2026

Emerging research suggests that keeping our bones strong may benefit the brain as much as it protects against osteoporosis and its complications.

A recent study looking at a specific bone biomarker, sclerostin found that higher levels were linked to cognitive decline in women, supporting the idea of cross-talk between the bone and the brain.

This adds to growing evidence for the bone-brain axis, highlighting how bone health may play a role in long-term cognitive wellness.

📖 [PMID: 38409606]

Magnesium is an important mineral for several processes in the body (over 600 actually)! And one emerging function of ma...
01/30/2026

Magnesium is an important mineral for several processes in the body (over 600 actually)!

And one emerging function of magnesium is in the realm of brain health

Higher dietary magnesium intake is linked with larger brain volumes and fewer white matter lesions, especially in women, suggesting magnesium may play a role in long‑term brain health

Do you get enough magnesium?

The Evanthea Trial tested a personalized, root-cause approach to cognitive health.It addressed nutrient status, chronic ...
01/28/2026

The Evanthea Trial tested a personalized, root-cause approach to cognitive health.

It addressed nutrient status, chronic infections, inflammation, metabolic health, and more.

The results were impressive: participants showed statistically significant improvements in memory, executive function, processing speed, and overall cognition, while standard care showed little to no improvement

This study marks a huge advancement in understanding cognitive decline!

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T2G

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