11/28/2025
Does It Matter When You Take Your Blood Pressure Meds?
Sometime last year, I shared that timing likely doesn't matter and that morning vs evening dosing showed no difference in outcomes like heart attack or stroke.
That’s still mostly true … but there’s new data worth discussing.
🔍 The OMAN trial (2025) has reignited the conversation by showing:
– Slightly better 24-hour blood pressure control with bedtime dosing
– No increase in side effects or hypotension
– BUT OMAN was short (12 weeks) and didn’t assess long-term outcomes
🧠 Prior trials (like TIME and BedMed) had thousands of participants and longer follow-ups and were considered to be the final word at the time. They found:
– No difference in heart attacks, strokes, or deaths
– Some modest BP reductions with night dosing BUT not enough to change clinical outcomes
What’s the bottom line?
👉 Compliance still wins.
Take your meds when you’re most likely to remember. For some, that’s morning. For others, night.
🌙 And if you’re a true night owl, there's emerging evidence that syncing meds with your personal rhythm might offer extra benefits — but that’s still being studied.
💬 As always, talk to your provider before making any changes. What matters most is consistency.
