04/12/2026
https://pubmed.ncbi.nlm.nih.gov/41904318/
Efficacy, safety, route of administration of midazolam and diazepam for pediatric status epilepticus: systematic review, meta-analysis, and trial sequential analysis
"Midazolam is the preferred first-line anticonvulsant for pediatric status epilepticus."
Midazolam demonstrates superior efficacy over diazepam, particularly via buccal and intramuscular routes. It addresses critical prehospital delays by bypassing the high failure rates associated with pediatric vascular access. Intramuscular administration matches intravenous efficacy while enabling i...
