Cannabis Science Information

09/15/2025

05/14/2025

Highlights

•The Endocannabinoid System (ECS) is a physiological system essential for maintaining CNS homeostasis and regulating neurological functions.

•ECS and cannabinoid receptors (CBRs) play a crucial role in several neurological disorders.

•The cannabinoid type 2 receptor (CB2R) is a promising therapeutic target due to its neuroprotective effects without CB1R-related psychotropic effects.

•Although the effects of CB2R agonists are numerous, clinical studies conducted to date are still limited.

05/14/2025

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Results: The meta-analysis revealed a significant consensus supporting the use of medical cannabis in the categories of health metrics, cancer treatments, and cancer dynamics. The aggregated correlation strength of cannabis across all cancer topics indicates that support for medical cannabis is 31.38× stronger than opposition to it. The analysis highlighted the anti-inflammatory potential of cannabis, its use in managing cancer-related symptoms such as pain, nausea, and appetite loss, and explored the consensus on its use as an anticarcinogenic agent.
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Background: Growing bodies of evidence suggest that cannabis may play a significant role in both oncological palliative care and as a direct anticarcinogenic agent, but classification as a Schedule I substance has complicated research into its therapeutic potential, leaving the state of research sca...