12/15/2025
🚨Just published in open-access in Cell Reports by Cell Press: our latest work on how brain activity evolves across the human lifespan.
We analyzed resting-state (MEG) data from more than 1,000 people aged 4-89 to understand how individualized neurophysiological traits change with age.
We found that brain activity is more similar to one another in childhood, but become increasingly unique through development and into adulthood.
The brain regions that most distinguish individuals also shift with age, with sensorimotor areas playing a bigger role in adulthood. Importantly, these changes align with patterns of gene expression tied to neural signaling, suggesting that genetic influences on brain individuality strengthen over time.
These insights deepen our understanding of how the biological foundations of brain function unfold across life and highlight new avenues for studying individual differences in health and cognition.
👏🙏🏼 Jason da Silva Castanheira, Alex Wiesman and Margot Taylor!
The Neuro, Centre de recherche du CHUM