Magic Nanaimo

12/16/2025

The Czech Republic is letting doctors prescribe magic mushrooms.

According to a report published by Czech News Agency (CTK), the country will allow medical psilocybin starting next year following an amendment to their Criminal Code.

This marks a growing recognition of the therapeutic potential of psychedelics.

The Czech model was explicitly inspired by Australia's framework, which has allowed controlled therapeutic use of M**A and psilocybin since 2023.

It's the same approach they used with medical cannabis back in 2013, and apparently that experience taught them a lot about how to do this carefully.

But here's the catch: sessions could cost thousands of pounds, and insurance reimbursement isn't figured out yet.

The mental health director in Prague said breakthrough treatments only for rich people are "unacceptable."

There's a weird legal gap too.

Doctors can prescribe it in clinics, but a friend keeping you safe during a trip might technically be criminal under old drug laws.

This could be an important step for Europe.

Czech Republic are building real safeguards while helping people who need it.

The test is whether they solve the money problem, because medicine only for the wealthy isn't really medicine.

From High and Polite FB page

12/16/2025

Here’s a weird collision nobody saw coming: people on GLP-1 weight-loss drugs like Ozempic are taking mushrooms and… nothing happens.

Trips take forever to start, feel dull, or don’t show up at all.

Joe Moore from Psychedelics Today noticed the pattern first, and it’s becoming a real issue in 2025.

GLP-1 drugs slow digestion right down. That’s great for appetite control, but terrible for mushrooms because your body needs to convert psilocybin into psilocin in the gut.

When digestion crawls, that conversion becomes unpredictable.

People end up waiting hours, getting muted effects, or thinking they’re non-responders.

The psychedelic community quickly got creative.

One solution is sublingual psilocin - i.e putting the active compound under your tongue so it skips the gut entirely.

The onset is faster, cleaner, and more predictable, especially for anyone whose digestion is slowed by medication. It’s not new tech, but it works.

The more accessible fix is the classic lemon tek.

Dr Erica Zelfand has been using it with retreat clients on GLP-1 meds: soak mushrooms in lemon juice for 15 minutes, let the acid convert psilocybin into psilocin, then drink.

It bypasses the sluggish stomach and gives a consistent, reliable experience.

What’s interesting is that this whole discovery didn’t come from labs. It came from people comparing notes in private groups.

It’s a reminder that psychedelic culture evolves from the ground up.

If you’re on GLP-1 meds, just know your usual dosing may not apply. We’re in new territory, and everyone’s still learning.

From the page, High and Polite.

12/16/2025

Researchers just published what might be the most detailed look yet at how psychedelics actually work.

Tracing neuron by neuron, they found exactly how psilocybin reshapes the brain's wiring.

And the results are beautifully weird.

Instead of relying on fMRI scans, the researchers used a viral tracing technique to literally map which neurons connect to which after a single dose of psilocybin.

Think Google Maps for the brain.

Psilocybin, they found, adds new “roads” only in certain places, and only between specific circuits.

Surprisingly, psilocybin affects two major neuron types in opposite ways.

It weakens cortical feedback loops linked to overthinking, while strengthening pathways that turn sensation into action.

When one circuit turns up, the other turns down, like a built-in rebalancing act.

That matters for depression. Rumination is basically the brain stuck talking to itself.

Psilocybin appears to quiet those loops while reconnecting the brain to sensory reality.

Less endless internal chatter, more presence.

And crucially, this rewiring depends on what’s active during the trip.

So the experience matters a lot.

Psilocybin opens a window for change, but what fills that window shapes the outcome.

That helps explain why one guided session can have lasting effects.

It also suggests there’s potential to "sculpt" this plasticity by manipulating activity during the psychedelic state.

Watch this space.

From the page High and Polite.

12/15/2025

I'd love to get my hands on some of this.

A mysterious Asian mushroom triggers vivid sightings of tiny beings across cultures, blending folklore, biology, and an unexplained perceptual effect.

12/14/2025

12/14/2025

12/14/2025

12/14/2025

12/04/2025

Fungi never cease to amaze me!

Scientists are now exploring how mushrooms can form the foundation of new computing systems, literally growing their own memory. The mycelial networks that have sustained ecosystems for hundreds of millions of years may soon inspire sustainable, living technologies.

Nature is the ultimate innovator. The more we listen and learn from the fungal kingdom, the more we realize how much wisdom it holds!

Read more: https://www.earth.com/news/future-computers-could-grow-their-own-memory-from-mushrooms/