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08/07/2021
03/16/2021

Everyone who has had a sore throat, rash, hives, or a sprained ankle knows about inflammation. Those are normal appropriate responses of our defense system to infection or trauma. We need inflammation to survive.⁣⁣
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The trouble occurs when that defense system runs out of control, like a rebel army bent on destroying its own country. Most people are familiar with overactive immune responses and too much inflammation in common conditions like allergies, rheumatoid arthritis, autoimmune disease or asthma. But few people know that hidden inflammation run amok is at the root of all chronic illness: heart disease, obesity, diabetes, dementia, depression, cancer and even autism.⁣⁣
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We may feel healthy, but if this inflammation is raging inside of us, then we have a problem.⁣⁣
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So what is the best way to control inflammation while we’re still upstream? First, identify the triggers and causes of inflammation, and then help the body’s natural immune balance reset by providing the right conditions for it to thrive.⁣⁣
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Everyone is treating the downstream effects of inflammation, instead of addressing the cause: multiple problems that are really linked together by inflammation.⁣⁣
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Once you figure out the cause and get rid of it, how do you live an anti-inflammatory lifestyle? Here is what I recommend. It’s disarmingly simple, but an extraordinarily effective way. Here are 7 ways:⁣⁣
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1. Eat a whole food, high fiber, plant-based diet which is inherently anti-inflammatory.⁣⁣
2. Eat healthy fats from olive oil, nuts, avocados and omega 3 fats from small fish like sardines, herring, sable, and wild salmon.⁣⁣
3. Exercise.⁣⁣
4. Learn to actively relax to engage your vagus nerve, the powerful nerve that relaxes your whole body and lowers inflammation, by doing yoga, meditation, deep breathing or even taking a hot bath.⁣⁣
5. If you have food allergies, find out what they are and stop eating them.⁣⁣
6. Take probiotics (“good bacteria”) daily to help your digestion to improve the healthy bacteria in your gut which reduces inflammation.⁣⁣
7. Take a multi-vitamin and mineral supplement which helps reduce inflammation.⁣

10/13/2020
07/22/2020
05/26/2020

Intermittent Fasting is a type of diet in which one regularly forgoes food for a certain period of time, usually somewhere between 14 and 18 hours. While it’s been known that IF increases the rate of hippocampal neurogenesis, the precise nature of the relationship is still poorly understood.

One study using mice revealed an increased activation of the Notch signaling pathway, a type of cell-to-cell communication that’s important to cell differentiation, the process by which immature cells, like stem cells, take on a permanent form and function. In humans, Notch signaling is related to hippocampal neuroplasticity, the brain’s ability to create new connections, allowing us to learn and form new memories.

Sometimes less is more!

Source: https://onlinelibrary.wiley.com/doi/full/10.1002/brb3.1444

04/15/2020

Adults with traumatic brain injuries (TBIs) are more likely to develop diabetes and other endocrine system disorders. But scientists know far less about how this link plays out in children.A new study of Arizona children, published in the journal Frontiers in Neurology, seeks to address that issue.

04/15/2020

As I have been saying one othe most important things you can do during this crisis is to keep your brain healthy and balanced. The brain is the master regulator of the immune system, the left brain activates the immune system and the right brain dampens it. I will present more research on this , there is a ton of research on this over the last 30 years this is just one small example. Kids and adults with left brain deficits and high right brain are at risk. If your kid or you have a learning disability, dyslexia,processing disorder , dysgraphia , bipolar, dyspraxia, PTSD, Depression all are left brain deficits . Make sure you don’t stop stimulating their brains !!!

04/14/2020

Nice Summary of a lot of our discussions

04/09/2020

The eye-tracking technology used to measure VSP eye movements is able to provide a timely and objective method of differentiating between individuals with moderate and severe levels of TBI.

01/10/2020

The shearing forces of a concussion or traumatic brain injury can cause damage to the axons of nerves in the brain.

Twisting or tearing of axons can disrupt and slow down communication between nerves which can lead to a whole host of symptoms.

However, just like bad traffic on a main highway, these nerves can find alternate routes to reach their destination. It may be slow at first, but over time, efficiency and repetition of these “side roads” can lead to faster communication and restore function closer to normal, if not all the way!

12/27/2019

Persistent problems 1 year after mild traumatic brain injury: a longitudinal population study in New Zealand

Conclusion:

Although some people make a spontaneous recovery after mTBI, nearly half continue to experience persistent symptoms linked to their injury. Monitoring of recovery from mTBI may be needed and interventions provided for those experiencing persistent difficulties. Demographic factors and medical history should be taken into account in treatment planning.

Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684031/?report=reader

Image: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306025/figure/F2/?report=objectonly

11/03/2019

Is your vagus nerve causing leaky gut? These are the 4 strongest vagus exercises to improve gut function.

11/02/2019

Microglia in the TBI brain: The good, the bad, and the dysregulated

Quote:
"As the major cellular component of the innate immune system in the central nervous system(CNS) and the first
line of defense whenever injury or disease occurs, microglia play a critical role in neuroinflammation following a
traumatic brain injury (TBI).

In the injured brain, microglia can produce neuroprotective factors, clear cellular debris and orchestrate neurorestorative processes that are beneficial for neurological recovery after TBI. However,
microglia can also become dysregulated and can produce high levels of pro-inflammatory and cytotoxic mediators
that hinder CNS repair and contribute to neuronal dysfunction and cell death.

The dual role of microglial activation in promoting beneficial and detrimental effects on neurons may be accounted for by their polarization state and functional responses after injury. In this review article, we discuss emerging research on microglial activation phenotypes in the context of acute brain injury, and the potential role of microglia in phenotype-specific neurorestorative processes such as neurogenesis, angiogenesis, oligodendrogenesis, and regeneration.

We also describe some of the known molecular mechanisms that regulate phenotype switching and highlight new therapeutic approaches that alter microglial activation state balance to enhance long-term functional recovery after TBI.

An improved understanding of the regulatory mechanisms that control microglial phenotypic shifts may advance our knowledge of post-injury recovery and repair, and provide opportunities for the development of novel
therapeutic strategies for TBI".

Reference:
Loane, D. J., & Kumar, A. (2016). Microglia in the TBI brain: The good, the bad, and the dysregulated. Experimental Neurology, 275, 316–327. doi:10.1016/j.expneurol.2015.08.018

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