Ask Aubry Tager

11/16/2022

Facing a health issue of any kind can be challenging, but for those diagnosed with ALS, a progressive and fatal neurological disease, each day represents precious time they have with family and friends.

10/04/2021

5 facts about Dopamine:

1. Dopamine informs your decision making.
2. Dopamine modulates behavior based on learned experiences.
3. Dopamine plays a role in motivational mindset.
4. Dopamine is responsive to novelty.
5. Tyrosine is a building block to dopamine.

08/07/2021

07/28/2021

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From: https://www.researchgate.net/publication/316583964_Photobiomodulation_and_the_brain_-_has_the_light_dawned

07/14/2021

Paper for purchase: https://pubmed.ncbi.nlm.nih.gov/32029015/

07/12/2021

Glutamate is the major excitatory neurotransmitter in neuronal and glial cells of the mammalian central nervous system (CNS).

However, after TBI, glutamate increases to toxic levels, causing further damage and leading to ‘glutamate excitotoxicity’

In addition to damaging neurons, glutamate can damage glial cells, such as astrocytes and oligodendrocytes.

Astrocytes are the most abundant glial cells in the CNS and can transport nutrients, hold neurons, and participate in neurotransmission.

During brain injury, neuronal survival is strongly affected by the functions of astrocytes, such as glutamate uptake, release of glutamate, and the release of substrates for neuronal energy metabolism, suggesting that the damage caused to astrocytes following TBI adversely affects patient outcomes.

Therefore, devising a strategy to protect astrocytes from cell death after TBI is crucial.

Source: https://www.nature.com/articles/cddis2014123

03/16/2021

Everyone who has had a sore throat, rash, hives, or a sprained ankle knows about inflammation. Those are normal appropriate responses of our defense system to infection or trauma. We need inflammation to survive.⁣⁣
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The trouble occurs when that defense system runs out of control, like a rebel army bent on destroying its own country. Most people are familiar with overactive immune responses and too much inflammation in common conditions like allergies, rheumatoid arthritis, autoimmune disease or asthma. But few people know that hidden inflammation run amok is at the root of all chronic illness: heart disease, obesity, diabetes, dementia, depression, cancer and even autism.⁣⁣
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We may feel healthy, but if this inflammation is raging inside of us, then we have a problem.⁣⁣
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So what is the best way to control inflammation while we’re still upstream? First, identify the triggers and causes of inflammation, and then help the body’s natural immune balance reset by providing the right conditions for it to thrive.⁣⁣
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Everyone is treating the downstream effects of inflammation, instead of addressing the cause: multiple problems that are really linked together by inflammation.⁣⁣
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Once you figure out the cause and get rid of it, how do you live an anti-inflammatory lifestyle? Here is what I recommend. It’s disarmingly simple, but an extraordinarily effective way. Here are 7 ways:⁣⁣
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1. Eat a whole food, high fiber, plant-based diet which is inherently anti-inflammatory.⁣⁣
2. Eat healthy fats from olive oil, nuts, avocados and omega 3 fats from small fish like sardines, herring, sable, and wild salmon.⁣⁣
3. Exercise.⁣⁣
4. Learn to actively relax to engage your vagus nerve, the powerful nerve that relaxes your whole body and lowers inflammation, by doing yoga, meditation, deep breathing or even taking a hot bath.⁣⁣
5. If you have food allergies, find out what they are and stop eating them.⁣⁣
6. Take probiotics (“good bacteria”) daily to help your digestion to improve the healthy bacteria in your gut which reduces inflammation.⁣⁣
7. Take a multi-vitamin and mineral supplement which helps reduce inflammation.⁣

11/15/2020

Potential nutritional therapies that could be of benefit in the treatment of TBI:

1. Curcumin: There is some evidence of improved motor & learning performance, blood–brain barrier integrity, cognition & reduced cerebral edema in brain injured animals.

2. Glutathione: There is some evidence that this nutrient reduces ROS levels & improves brain injury markers.

3. Zinc: This mineral is required in central nervous system enzyme functions. Zinc is released in the synaptic cleft of the brain where neuroreceptor activity is modulated. Excess release of zinc contributes to neural cell death. Zinc deficiency could exacerbate cell death in TBI. Patient trials with zinc show positive effects in severe closed-head injuries. More research is indicated.

4. Vitamin K2: This vitamin is neuroprotective.

5. Magnesium: This mineral is usually depleted in TBI. It could have a neuroprotective effect & decrease glutamate damage by regulating calcium entry into postsynaptic neurons.

6. Vitamin D: This vitamin binds DNA response involved in regulation of gene transcription, differentiation & neural function in the brain

7. DHA/EPA: Evidence shows an anti-inflammatory & neuroprotective benefit against brain injuries.

8. Choline: This is an anti-inflammatory & antioxidant that could support a decrease in calcium-mediated cell death, which is common in TBI.

More info: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580364/ #!po=69.8529

10/17/2020

Dopamine Facts 🧠🏃🏼‍♂️🤗