11/03/2025
New Review Supports Natural Remedies for Irritable Bowel Syndrome
Of all the many disorders of the gastrointestinal tract, irritable bowel syndrome (IBS) is the most common, affecting as many as 11%-15% of all people. 35 million Americans suffer from IBS. The conventional approach focusses only on symptom relief. Nature can do better!
Several supplements have proven their effectiveness for IBS in studies. A just published comprehensive review has examined the current research on natural remedies.
The researchers note that, since many herbs modulate intestinal motility, inflammation and pain, they may offer a more holistic approach than the symptom management of pharmaceuticals. They also note the advantage of the safety of the herbs.
Several studies have proven the effectiveness of peppermint oil, including a number of meta-analyses, and a review that demonstrated improvement in IBS symptoms when compared to placebo or drugs (Am J Health Syst Pharm 2016;73(2):22-31). A peppermint-caraway oil combination is superior to the drug cisapride (Arneimittlforschung 1999;49:925-32).
The new review explains that peppermint oil has many properties that could contribute to its ability to improve IBS. It says that peppermint oil is “a promising treatment” that has proven its efficacy in multiple controlled studies. It highlights a recent study in which peppermint oil improved people’s global assessment, IBS severity score, stool frequency and form.
Curcumin is another herbal supplement that the review says addresses IBS in multiple ways. It highlights a recent systematic review of 26 studies that demonstrated its effectiveness for IBS (Phytother. Res. 2024;38:2687–2706).
Fennel is effective for colic and digestive problems and, the researchers say, could be effective for IBS. They point to a study of fennel oil and curcumin that
showed that the herbal combo reduces abdominal pain and other IBS symptoms and improves quality of life (J. Gastrointest. Liver Dis. 2016;25:151–157). A closer look at that study reveals the power of the herbal combo. There was a 50.5 point improvement on the IBS Symptom Severity Score compared to 28.85 on placebo. Significantly more people on the herbs were symptom free: 25.9% versus 6.8%. They also had a significantly greater improvement in abdominal pain: 63.8% pain reduction versus 27.1%. Quality of Life scores were also significantly higher in the herb group: 17.4 versus 7.7.
Finally, the review found that aloe vera also works. It pointed to a pooled analysis of 2 studies that found that aloe extract significantly reduces symptom severity, reduces the severity and frequency of abdominal pain and improves response rates (Ther. Adv. Gastroenterol. 2021;14:17562848211048133). Though not mentioned in the review, another meta-analysis of aloe and IBS that included 3 controlled studies also found that aloe is superior to placebo with more people responding and a significantly greater improvement in symptoms (J Neurogastroenterol Motil 2018;24(4):528-535).
The review concludes that “several herbal treatments, particularly peppermint oil, have demonstrated efficacy in multiple randomized controlled trials, providing a relatively robust rationale for their use in IBS management.”
Int J Mol Sci. 2025 Sep 24;26(19):9345.