10/02/2025
"human body is unlike a machine where you can independently tweak systems. Aspirin is indicated in patients with chronic coronary disease. But when this patient also has a reason to take oral anticoagulants, the combination of the two drug classes is not simply the sum of two beneficial therapies"
Many patients have indications for both aspirin and anticoagulation. The AQUATIC trial from ESC showed an increased risk of bleeding and mortality from the dual pathway therapy. Will practice change?