04/23/2020
The immunity boost from proper nutrition, exercise and sunlight is amazing. Many people need to rethink the danger of LDL cholesterol and sunshine.
While you are social distancing get active outside.
Be healthy everyone!
Vitamin D is made from LDL cholesterol when it is activated by 312 nm UVB light. LDL sterol then become a innate immunity secosteroid which turns on over a 1000 genes in your body to fill your blood plasma with over 1000 immune chemicals that format a proper innate immune repsonse. This is how and why sunlight becomes nature's ultimate vaccine against invading pathogens. Vitamin D is a natural antiviral/antibiotic that assists WBCs in clearing infections. It does this by stimulating immune cells to make a protein called cathelicidin in our skin. This does not happen well in our gut, but works like a charm in our skin with UV and IR exposure. People forget that the most T cells in humans are found in our skin awaiting to be activated by sunlight. This is why most viral infections respond to sunlight. This protein is found on T cells within our skin, macrophages, neutrophils, and on our epithelial cells in our guts and respiratory system. It actually helps defend us from viruses and bacteria all the time when its optimized. In our gut linings, it also activates the T regulator cells to protect the intestinal lining and the GALT that lies right behind the brush border. It is critical in optimizing Macrophages to avoid diseases like secondary HLH.
C-19 alters mitochondrial biology to innactivate COX's heme protein to cause massive light release that leads to cytokine storms ... C-19 knocks the hell out of the inner mitochondrial membrane in cells of the immune system called macrophages, T regulator, and NK cells. Therefore these cells liberate more ELF-UV light due to their mitochondrial failure and they cannot work properly. This change is inducible in those immune cells because of defects in the uncoupling proteins and poor utilization of oxygen. This leads to more ROS and more ELF-UV light release. These cells become overactive, causing too much inflammation = death in those people you don't expect based on the data you gained in round one of C-19.
This is how kinetic proofreading of light goes awry in diseases linked to low Vitamin D levels like HLH.
The light required for this activation may come from the prokaryotes in our gut microbiome who naturally release large amounts of light. Our enterocytes have to contain DHA in their cell membranes to decipher the signal properly. It now appears that low vitamin D status in the gut maybe a huge risk factor for the development of simian viruses, Coronaviruses, and HIV general infection.
Another major immune affect of Vitamin D is that is has the ability to block intracellular signals of NF Kappa beta and of TNF alpha. Both of these chemicals are part of the machinery that causes up-regulation of the stressful cellular response mechanisms in many pathologic diseases like sepsis, multi-organ system failure, HLH, cancer, autoimmunity and in obesity. This is why people with comorbidities are being attacked by this type of virus. The people in the tropics have a huge advantage if they get their skin in the game.
https://www.marketwatch.com/story/this-stunning-chart-shows-the-coronavirus-spreading-slowly-in-tropical-countries-2020-03-17
