11/07/2025
The era when ANOCA (Angina with Non-Obstructive Coronary Arteries), INOCA (Ischemia with Non-Obstructive Coronary Arteries), and MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries) were considered mere “diagnoses of exclusion” is over.
Contemporary cardiology now recognizes them as distinct clinical entities, each with specific pathophysiological mechanisms, microvascular dysfunction, vasospasm, or plaque disruption, requiring targeted evaluation and management.
The key is not a generic approach, but a mechanism-driven workup using functional coronary testing or advanced imaging to clarify the underlying cause and guide tailored therapy.
Myocardial infarction with