11/14/2025
The brain also heavily relies on ATP, and creatine plays a major role there, too. But your muscles are greedy, taking up most of the creatine you supplement with. So for creatine to have any significant cognitive benefit, you may need closer to 10 grams of creatine a day. According to Darren Candow, PhD, CSEP-CEP, a leading researcher on creatine, 10 grams of creatine per day, split into two doses, improved brain energy metabolism, processing speed, and memory, especially when under stress, like during sleep deprivation.
Muscles are greedy with creatine, but this dose ensures your brain gets its fair share.