Krembil Brain Institute

01/16/2026

📰✨ Congratulations to Dr. Valeria Ramaglia, Scientist with the Krembil Brain Institute at UHN, on her recent interview with La Repubblica, an Italian newspaper!

During the interview, Dr. Ramaglia shared findings from a recent UHN–UofT study she co-led with Dr. Jennifer Gommerman, which identified a biomarker linked to the inflammation that drives progressive MS. 🔬🧠

Click the link below to read the interview! ⬇️

🔗: https://linktr.ee/krembil

01/13/2026

🎉✨ Please join us in celebrating Dr. Michael Fehlings, Senior Scientist with the Krembil Brain Institute at UHN, who has been awarded $250,000 in funding from the Christopher & Dana Reeve Foundation and Spinal Research!

Only 4 preclinical studies received this grant, focused on developing new treatments for traumatic spinal cord injury (SCI).

🧠 Dr. Fehlings’ project will advance a new stem cell–based strategy to repair the spinal cord by:�
1️⃣ Producing an enzyme that helps remove scar tissue blocking nerve regrowth�
2️⃣ Releasing a supportive protein that protects and nourishes nerve cells

Interested in learning more about his study and the grant? Click the 🔗 below!

🔗: https://linktr.ee/krembil

01/13/2026

A Toronto‑based team from University Health Network's Krembil Brain Institute and U of T Medicine has uncovered a disease mechanism that drives progressive (MS) and identified a potential biomarker that could help clinicians detect the hard‑to‑measure inflammation linked to disease progression.

Using a newly developed model of grey matter injury, the researchers mapped out how immune proteins, CXCL13 and BAFF, behave in progressive MS. They found that the ratio of these proteins may serve as a marker for leptomeningeal inflammation, a hallmark of advancing disease.

This collaborative discovery not only sheds light on why current therapies may fall short in progressive MS, but it also points toward more precise ways to diagnose the condition and better identify patients who may benefit from emerging treatments.

A significant step forward for MS research—powered by innovative science and a strong partnership between UHN and U of T.

🔗 Read more: https://www.uhnresearch.ca/news/new-clues-multiple-sclerosis

UHN Foundation, Canadian Institutes of Health Research MS Canada, National Multiple Sclerosis Society

01/13/2026

01/12/2026

📖✨Congratulations to Dr. Valeria Ramaglia, Scientist at UHN’s Krembil Brain Institute, on her recent publication in Nature Immunology. The study was also co-led by Dr. Jennifer Gommerman from UofT's Temerty Faculty of Medicine.

The UHN-UofT collaboration uncovers a biomarker linked to inflammation driving progressive MS. 🧠

Click the link below to read the study! ⬇️

🔗: https://linktr.ee/krembil

01/12/2026

📰✨ Congratulations to Dr. Hance Clarke, Clinician Investigator at UHN’s Krembil Brain Institute, on his interview with CTV News last month!

Dr. Clarke shared his expertise on patients having to change their pain medications due to stock shortages.

Click the link below to read more! ⬇️

🔗: https://linktr.ee/krembil

12/23/2025

🎄✨On our final day of 12 Days of Krembil, we want to highlight our research showcase event, Krembil Science Jam!

The second annual Krembil Science Jam celebrated science through 10 TED Talk-style presentations from researchers at UHN’s UHN’s Krembil Brain Institute, Donald K. Johnson Eye Institute and Schroeder Arthritis Institute.

With topics ranging from Alzheimer disease and Parkinson disease to low vision, osteoarthritis, and mental illness and more, this event offered an exciting glimpse into the cutting-edge work happening every day at our institutes.

▶️ Watch the event via the 🔗 below ⬇️:

🔗: https://linktr.ee/krembil

12/22/2025

As 2025 comes to a close, we look forward to a new year full of opportunities to continue creating .

Happy holidays from Research at UHN

12/22/2025

🎄✨On day 11 of our 12 Days of Krembil, we want to highlight Dr. Anthony Lang, Senior Scientist at UHN’s Krembil Brain Institute!

In November, Dr. Lang was recognized among the world’s most highly-cited researchers! This distinction comes from Clarivate, a global leader in bibliometrics and analytics.

Learn more via the 🔗 below ⬇️:

🔗: https://linktr.ee/krembil

12/19/2025

🎄✨On day 10 of our 12 Days of Krembil, we want to highlight our wonderful trainees at UHN’s Krembil Brain Institute!

In April, we celebrated 25 years of the annual event, Krembil Research Day, which offers trainees a valuable opportunity to network and celebrate their research achievements.

Along with UHN’s Donald K. Johnson Eye Institute and Schroeder Arthritis Institute, the event hosted more than 200 trainees, faculty, and staff, and featured 76 posters and nine oral presentations.

Learn more about Krembil Research Day via the 🔗 below ⬇️:

🔗: https://linktr.ee/krembil

12/18/2025

🎄✨On day 9 of our 12 Days of Krembil, we want to highlight our researchers at UHN’s Krembil Brain Institute!

In January 2025, it was announced that several Krembil Investigators triumphed in the Fall 2024 CIHR Project Grant
Competition, helping to secure over $4.2M in funding.​

Learn more about this Project Grant competition via the 🔗 below ⬇️:

🔗: https://linktr.ee/krembil

12/17/2025

🎄✨On day 8 of our 12 Days of Krembil, we want to highlight Dr. Michael Fehlings, Senior Scientist at UHN’s Krembil Brain Institute!

In March, Dr. Fehlings was honoured with the King Charles III Coronation Medal in recognition of his contributions to medicine, science and advancements in spinal cord injury and neurotrauma.

Learn more about this prestigious award via the 🔗 below ⬇️:

🔗: https://linktr.ee/krembil