04/19/2026
Growing evidence suggests that cancer and neurodegenerative diseases share genes and biological pathways.
Multiple studies have found that people with Alzheimer’s have a significantly lower risk of developing cancer, and cancer survivors have a lower risk of developing Alzheimer’s.
A large meta-analysis reported that:
* Individuals with Alzheimer’s were about 47% less likely to develop cancer
* Cancer patients were about 39% less likely to develop Alzheimer’s
Other population studies have shown similar magnitudes:
* ~35–37% lower risk of Alzheimer’s in people with cancer
* ~42–50% lower risk of cancer in those with Alzheimer’s
This inverse association has been observed repeatedly across large cohorts and long-term studies and is considered robust, though not fully understood biologically.
This unusual pattern for cancer is similar to that seen in Parkinson’s disease.
The inverse relationship between cancer and Alzheimer’s has been reported in major peer-reviewed journals, including BMJ, Neurology, and JAMA Network Open, and has been confirmed by large cohort studies and meta-analyses.
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