11/21/2025
InMed has conducted several in vitro and in vivo studies to test the pharmacological effects of INM-901 in Alzheimer’s disease preclinical models with promising results demonstrating disease-modifying effects.
A summary of INM-901 preclinical study results:
➡️ Demonstrates neuroprotective effects by reducing cell death in an amyloid-beta-induced cytotoxicity study
➡️ Demonstrates significant reduction in inflammatory biomarkers associated with Alzheimer’s, including IFN-γ, TNF-α, IL-1β, KC-GRO, IL-2 & NfL
➡️ May have a direct impact on neuroinflammation independent of the influence of amyloid beta or tau aggregation
➡️ Demonstrates an ability to promote neurite outgrowth, signifying the potential to improve neuronal function, a potential breakthrough in the treatment of Alzheimer’s disease
➡️ Demonstrates a trend in improvement in cognitive function and memory, locomotor activity, anxiety-based behavior, sound awareness and neuronal function
➡️ Demonstrates robust bioavailability in in vivo models, achieving what is anticipated to be therapeutic levels of systemic exposure
➡️ Additional mRNA data supports the observations made in behavior studies in locomotor activity, cognition and memory.
More about InMed's INM-901 program here: https://www.inmedpharma.com/pharmaceutical/inm-901-for-alzheimers-disease/
$INM