Cytosurge AG

29/12/2025

Feed your brain too this winter, not just your belly. Hear about a breakthrough that changes how we study immunity.
Carmine Cristinzio (ETH Zurich, Prof. Annette Oxenius, ) shows how FluidFM enables the first single cell observation of asymmetric division in CD8 T cells, a phenomenon previously inferred only at population level.🔬

• Isolate sister cells immediately after asymmetric division
• Sample tiny amounts of cytoplasm to detect molecular differences
• Track fate over time: does one become memory while the other becomes effector?
• Prove, at single cell resolution, what hasn’t been directly seen before

“This lets us isolate cells right after division to determine if one becomes a memory cell while the other an effector cell, something never done before.”

This single-cell precision could reshape our understanding of immune memory formation.

More customer stories in the first comment 👇

23/12/2025

As 2025 comes to an end, we want to thank you for your trust and support. 💙
Your engagement with FluidFM technology, through publications, collaborations, and feedback, continues to inspire our work.

We look forward to entering 2026 with fresh energy, advancing single-cell analysis 🧬, precise gene editing 🛠️, and applications. 🚀
Wishing you a joyful holiday season and a great start to the new year. ❄️🎄
See you in 2026! 💙

#2025 #2026

22/12/2025

Season’s Greetings from CellEDIT
As 2025 comes to an end, we want to thank you for trusting with your gene editing projects this year. 💙
Your challenges and feedback have inspired us to refine our workflows and deliver precise, reliable results. 🧬🛠️
We look forward to 2026, continuing to support your research, advancing single-cell editing, and achieving new milestones together. 🚀
Wishing you a joyful holiday season and a fantastic start to the new year! ❄️🎄

#2025 #2026

19/12/2025

Newsletter: Cell-ebrating a Year of Precision 🧬❄️

Closing the hood on 2025? If generating your genome-engineered cell lines faced bottlenecks this year, like toxicity or low efficiency this year, our latest update is your blueprint for a better 2026.

Inside this edition: 🔬 The Advantage: Physics, not luck. ✅ Injection: Direct intranuclear delivery. ✅ Vector-Free: Pure RNP complexes. ✅ Precise Stoichiometry: Max editing, min toxicity.

Plus: 📖 Customer Stories: Featuring the latest work from Dr. Alessandro Penna, University of Padova, and Dr. Alfonso Calvo, Universidad de Navarra. 💥 Winter Offers: Exclusive end-of-year opportunities. 📅 Q1 Planning: Beat the January rush.

Read the full update here: 👇

Hello from CellEDIT, It’s been a year of breakthroughs, challenges, and, if you’re like most of us, a lot of time in the lab. As we approach the end of the year, we know you’re looking forward to closing the hood, taking off the lab coat, and enjoying some well-deserved downtime.

17/12/2025

❄️ Holiday Reading for Single-Cell Scientists ❄️

We’ve bundled our top Live-seq resources into one package, perfect for a quick catch-up or for elevating your single-cell studies in the new year. 🧬

In this edition, we explore Live-seq as a practical workflow, share new proof-of-concepts, and feature fresh interviews with researchers applying FluidFM in cancer biology. Plus, enjoy webinar replays and a few surprises under the Live-seq tree! 🎄

👉 Read the newsletter & subscribe on LinkedIn: https://bit.ly/4qjAOnT

As 2025 comes to a close, thank you for your trust and support. 💙 We look forward to advancing single-cell research together. 🚀

Hello from Cytosurge, As the winter break approaches, we’ve bundled our most useful Live‑cell sequencing (Live-seq) resources into one easy package, perfect for a quick catch‑up now or planning experiments for the new year. Live-seq Webinar 🎥 Catch the Replay & Download the Slides Dr.

17/12/2025

Last week, we kicked off the festivities with some fun on the ice ❄️⛸️, followed by our company year-end dinner. It was the perfect moment to pause and reflect on a year that challenged us, strengthened us, and reminded us of what and can achieve. 💪

Despite the hurdles, there was so much to celebrate (and laugh about!) as we continued advancing technology, supporting groundbreaking research, and enabling scientists to push boundaries. 🔬📈

Here’s to moving forward together, on and off the ice. 💙

A huge thank you to our team, partners, and supporters for being part of this journey. Let’s keep shaping the future of science! 🌟

15/12/2025

· Holiday Recap 🧬 Chapters 1–6 🎄
As the year wraps up, here’s a quick recap of our CellEDIT101 series on precision cell engineering ✨:
1. What is Single Cell Gene Editing? 🔬 Precise, clonal editing at the level that matters: one cell, one outcome.
2. What is Intra Nuclear Injection? 🎯 Direct, vector free CRISPR RNP delivery straight to the nucleus with force control.
3. Mastering RNP Stoichiometry in Multiplex Editing ⚖️ Tune gRNA/Cas ratios to coordinate multiple edits in one shot, reliably and reproducibly.
4. Overcome the “Hard” in Hard to transfect Cells 🛡️ Gentle delivery directly into the nucleus, making it ideal for developing cell lines in hard-to-transfect cells.
5. What is CRISPR? ✂️ Adapted from bacterial immunity, CRISPR uses a gRNA to guide Cas to DNA; the cell makes the change, knockouts, tweaks, or insertions.
6. iPSCs Editing: Precision Without Losing Pluripotency 🌱 Maintain stemness while achieving targeted edits with direct RNP delivery.

Browse the full recap (all chapters in one place) and tell us which topics you want next year 🎁🧪

Happy holidays, and see you in the lab in the new year! ❄️

11/12/2025

Pushing the size limits in single-cell biology. 🧫

Meet Spirostomum (“Spiro”), a unicellular organism (100–400× larger than an average mammalian cell) that contracts 14× faster than free fall and shows memory-like habituation after repeated stimulation. Researchers at the Georgia Institute of Technology want to understand how, so they turned to the OMNIUM for biopsies. 🔬

What we demonstrated:
• Live, non-destructive biopsies on Spiro
• OMNIUM handles large, dynamic cells with precision
• Spiros tolerate the biopsy procedure without harm
Watch the video to see the biopsy in action. 🎥

10/12/2025

Transcriptional journey of single living cells over time with on . 🧬⏱️
• Cytoplasmic “biopsy” keeps cells viable for longitudinal sampling
• Point and click OMNIUM workflow with precise extraction volumes
• Ultra low input RNA seq via Lexogen’s LUTHOR HD
Use it to study fate decisions, drug responses, neuron–astrocyte interactions during synaptogenesis, and much more....

📝 Apply to our Live seq Access Program for proof of principle studies on selected projects (QR code in the flyer, page 3)
🎥 Watch the webinar recording and access the slides via the QR codes in the flyer (page 4)

08/12/2025

CellEDIT Winter Sale ❄️
Vector-free, intra-nuclear CRISPR editing for hard-to-transfect cell lines — with guaranteed monoclonality.
Check feasibility & pricing via the CellEDIT Quoter. 👉 https://cytosurge.com/celledit-winter-offers?utm_source=linkedin&utm_medium=social_organic&utm_campaign=celledit&utm_term=winter

05/12/2025

Determine Today’s Transcriptome. Study Tomorrow’s Response. How? Cytosurge × Lexogen turned Live seq into the first end-to-end commercial live-cell sequencing workflow—now available to academic researchers and industry partners worldwide.
What you’ll learn:
• How subcellular biopsies capture the full transcriptome from living cells directly in the dish
• Repeated RNA reads from the same intact cell to track responses over time
• How to uncover causal links between molecular changes and phenotype for real decision-making
Speakers:
• Dr. Ludovica Rizzo, Applications Services Manager, Cytosurge
• Dr. Filippo Passardi, Product Manager, Lexogen

Access the replay, slides, and resources via the QR code on the last slide of the carousel 👇 or the link in the first comment 👇

04/12/2025

It’s that time of year again! 2025 Wrapped at Cytosurge. Explore the highlights of our year — from empowering researchers globally to breaking new boundaries in gene editing! 🚀