12/12/2022
INVITATION TO CONTRIBUTE:
https://www.elspub.com/journals/biofunctional-materials/special_issues/biopolymers-&-nanomaterials-and-their-application-in-medicine-&-dentistry
Special Issue Editor: Professor Dr. Ziyad S. Haidar, BioMAT'X (HAiDAR I+D+I) R&D&I, CiiB, F-ODO/F-MED, Universidad de los Andes, Santiago de Chile
Submission Deadline 30 JUNE 2023
About This Special Issue
A nano-bio-material may demonstrate different behaviours when compared to the same substance yet in bulk form. Meaning, a material could change when it goes from bulk to the nano-scale. This transformation could be revolutionary. Indeed, nanotechnology has, thus far, made it possible for us to create novel biomaterials that we could never formulate before via taking advantages of the physico-chemico-mechanical and cellular-biological (size and surface, amongst other parameters) effects. This has opened the door wide, enhancing the ability to deliver drugs in novel ways, for example, to treat critical clinical conditions. NanoMedicine and NanoDentistry, herein, is the application of nano-bio-technology to the field of medicine and dentistry, respectively, by the use of biopolymers and nanomaterials. The most common application involves employing nanoparticles and nanocapsules to enhance the action of encapsulant cells, proteins, genes, and drugs in the treatment of cancer, diabetes, skin, bone, teeth and the supporting tissues/structures to our jaws and dentition, to list a few. Current applications tend to re-enforce controlled drug delivery for disease diagnosis, monitoring, prevention, management, and therapy, via targeting and precision or personalized approaches and strategies. Hence, the incorporation of nanomaterials, bio-polymers and newly-discovered technologies to benefit human life and realize what was once thought to be un-attainable is the goal of practically any researcher, scientist and innovator. For controlled drug delivery, in particular, numerous nanomaterial and biopolymer characteristics of a delivery system are to be considered, including (but not limited to) dosage form, administration route, side effects, drug loading capacity, drug encapsulation efficiency, dose-response, pharmacokinetics, bio-distribution and fate, and patient compliance. Polymeric materials can be incorporated to better control the variables presented in a nano-scaled drug delivery system so that the drug, especially if poorly-soluble, can be safer and more effective/efficacious. This Special Issue will discuss the innovative nanomaterials and biopolymers being designed, synthesized, incorporated and used in formulating novel drug delivery systems for application in nanoMedicine and nanoDentistry, including cell/gene therapy, tissue engineering and regeneration indications. Experimental investigations and literature review articles are invited to discuss the different types of nanomaterials and biopolymers used, their preparation methods, safety and efficacy analysis, and potential translation from benchtop to bed-/chair-side. Contributions discussing different characterization methodologies and/or strategies and any evolving challenges/hurdles are also welcome.