13/01/2026
100 Degree-Level Research Topics for Medical Laboratory Science (MLS)
Carefully Grouped into Hematology, Bacteriology, and Parasitology
Ideal for HND & BSc Projects, with strong relevance to African and clinical laboratory settings
Medical Laboratory Science plays a critical role in disease diagnosis, management, and public health surveillance, especially in resource-limited settings. Selecting a relevant, feasible, and impactful research topic is therefore essential for producing meaningful academic work and practical laboratory solutions.
Below is a comprehensive and well-curated list of 100 research topics, thoughtfully categorized into Hematology, Bacteriology, and Parasitology, designed to meet degree-level research standards while addressing real-world health challenges commonly encountered in African healthcare systems.
A. HEMATOLOGY (34 Topics)
Hematology research remains central to understanding blood disorders, infections, chronic diseases, and nutritional deficiencies that significantly affect patient outcomes.
1. Prevalence of anemia among pregnant women attending antenatal clinics
2. Hematological changes in patients with malaria infection
3. Effect of sickle cell disease on complete blood count parameters
4. Assessment of iron deficiency anemia among adolescent girls
5. Coagulation profile in patients with liver disease
6. Platelet count variations in hypertensive patients
7. Hematological effects of HIV infection in adult patients
8. Impact of antiretroviral therapy on hematological parameters
9. Prevalence of thrombocytopenia among malaria patients
10. White blood cell patterns in bacterial versus viral infections
11. Hematological indices in patients with chronic kidney disease
12. Prevalence of sickle cell trait among blood donors
13. Blood group and Rhesus factor distribution among students
14. Hematological profile of patients with tuberculosis
15. Effect of nutritional status on hemoglobin levels in children
16. Evaluation of erythrocyte sedimentation rate (ESR) in inflammatory diseases
17. Coagulation abnormalities in diabetic patients
18. Comparative study of manual versus automated hematology analyzers
19. Prevalence of polycythemia among smokers
20. Effect of hookworm infection on hemoglobin concentration
21. Hematological findings in patients with typhoid fever
22. Red cell indices in iron deficiency anemia versus thalassemia
23. Frequency and pattern of blood transfusion reactions in a hospital setting
24. Hematological changes during pregnancy
25. Assessment of anemia among under-five children
26. Platelet indices in patients with cardiovascular diseases
27. Effect of chemotherapy on hematological parameters
28. Hematological profile of patients with sepsis
29. Correlation between CD4 count and hemoglobin levels in HIV patients
30. Prevalence of leukocytosis among febrile patients
31. Blood viscosity changes in sickle cell disease
32. Hematological alterations in patients with chronic alcohol use
33. Comparative study of capillary versus venous blood results
34. Knowledge and practice of voluntary blood donation among students
B. BACTERIOLOGY (31 Topics)
Bacteriology research is essential in combating infectious diseases, antibiotic resistance, and hospital-acquired infections, which are major public health concerns.
35. Bacterial pathogens associated with urinary tract infections
36. Antibiotic susceptibility pattern of *Escherichia coli* isolates
37. Prevalence of Staphylococcus aureus in wound infections
38. Detection and prevalence of methicillin-resistant Staphylococcus aureus (MRSA)
39. Bacterial contamination of hospital surfaces
40. Prevalence of typhoid fever among febrile patients
41. Antibiotic resistance patterns of clinical bacterial isolates
42. Bacterial causes of diarrhea among children
43. Isolation and identification of Salmonella species from stool samples
44. Bacteriological analysis of drinking water sources
45. Prevalence of bacterial vaginosis among women of reproductive age
46. Bacterial profile of lower respiratory tract infections
47. Nosocomial bacterial infections in hospitalized patients
48. Effect of inappropriate antibiotic use on resistance development
49. Isolation of Klebsiella pneumoniae from sputum samples
50. Bacterial contamination of laboratory equipment
51. Prevalence of Helicobacter pylori infection among dyspeptic patients
52. Comparison of culture methods and rapid diagnostic tests
53. Bacterial flora of mobile phones used by healthcare workers
54. Antimicrobial activity of selected medicinal plant extracts
55. Prevalence of Pseudomonas aeruginosa in burn wound infections
56. Bacteriological quality of street-vended foods
57. Prevalence of ESBL-producing bacteria in clinical isolates
58. Bacterial pathogens associated with neonatal sepsis
59. Effectiveness of disinfectants against hospital-acquired bacteria
60. Bacterial contamination of blood bank units
61. Prevalence of sexually transmitted bacterial infections
62. Bacterial causes of otitis media
63. Antibiotic sensitivity pattern of Streptococcus pneumoniae
64. Knowledge and awareness of antibiotic resistance among patients
65. Bacteriological assessment of hand hygiene practices among healthcare workers
C. PARASITOLOGY (35 Topics)
Parasitology research is particularly vital in tropical regions, where malaria and intestinal parasites continue to impact morbidity, mortality, and economic productivity.
66. Prevalence of malaria among febrile patients
67. Intestinal parasitic infections among school-aged children
68. Prevalence of Plasmodium falciparum infection in pregnant women
69. Effect of malaria infection on hemoglobin levels
70. Parasitic contamination of vegetables sold in local markets
71. Prevalence of helminth infections among rural dwellers
72. Co-infection of malaria and typhoid fever
73. Intestinal parasitic infections among food handlers
74. Prevalence of schistosomiasis in riverine communities
75. Diagnostic accuracy of rapid diagnostic test kits for malaria
76. Comparison of microscopy and RDTs in malaria diagnosis
77. Prevalence of giardiasis among children
78. Intestinal parasitic infections in HIV-positive patients
79. Prevalence of soil-transmitted helminths
80. Parasitic infections among immunocompromised patients
81. Effect of deworming programs on parasite prevalence
82. Seasonal variation of malaria infection
83. Knowledge, attitude, and preventive practices of malaria among households
84. Prevalence of Entamoeba histolytica infection
85. Parasitic infections in patients with chronic diarrhea
86. Relationship between malaria parasite density and disease severity
87. Intestinal parasitic infections and nutritional status of children
88. Parasitic contamination of water sources
89. Prevalence of toxoplasmosis among pregnant women
90. Blood parasites among blood donors
91. Diagnostic challenges of mixed parasitic infections
92. Prevalence of onchocerciasis in endemic communities
93. Parasitic causes of eosinophilia
94. Malaria prevalence among under-five children
95. Effect of insecticide-treated bed nets on malaria prevalence
96. Intestinal parasitic infections among prison inmates
97. Parasitic infections in diabetic patients
98. Knowledge of parasitic diseases among students
99. Prevalence of strongyloidiasis in rural communities
100. Laboratory diagnosis of parasitic infections: challenges and future prospects
