13/10/2025
Enterovirus 71 (EV71) is a major pathogen causing hand, foot and mouth disease (HFMD), a highly contagious illness that poses severe risks to human health, especially children under 5. According to the World Health Organization (WHO), HFMD outbreaks are common in the Asia-Pacific region, with EV71 responsible for over 80% of severe HFMD cases. Unlike other enteroviruses, EV71 often leads to life-threatening complications, including viral meningitis, encephalitis, myocarditis and acute flaccid paralysis. Each year, tens of thousands of children are hospitalized due to EV71 infection, and a small but significant number die from rapid disease progression, making timely diagnosis critical to reducing harm.
EV71 spreads primarily through close contact: via respiratory droplets, contaminated hands, toys, food or surfaces. Its early symptoms are easily confused with common childhood illnesses, such as fever (38 - 40°C), sore throat and loss of appetite--followed by characteristic rash or blisters on the hands, feet, mouth and buttocks within 1 - 2 days. Severe cases rapidly develop neurological signs (e.g., vomiting, limb tremors, lethargy) or respiratory distress, requiring emergency care. To address the need for fast diagnosis, the EV71 IgM Rapid Test Cassette (Whole Blood/Serum/Plasma) was developed--a rapid chromatographic immunoassay for qualitative detection of EV71 IgM antibodies in human whole blood, serum, or plasma. Its key advantages include:
Fast Results: Provides quick diagnosis within minutes.
Ease of Use: Requires no complex procedures or equipment.
High Accuracy: Offers reliable results to ensure proper diagnosis.
Easy Visual Interpretation: Results are straightforward to read.
Specimen: Whole blood, serum or plasma.
Portable: Suitable for use in various settings.
Cost-Effective: Affordable for healthcare solutions.
Supports Timely Treatment: Facilitates early intervention to prevent complications.
In summary, this test cassette is a vital tool for EV71 infection control. It bridges the gap between delayed traditional lab tests and urgent clinical needs, enabling early diagnosis to reduce severe complications and mortality. For communities prone to HFMD outbreaks, it strengthens public health surveillance, protects vulnerable children and plays a key role in minimizing the societal impact of EV71-related illnesses.
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