Laboratory of Experimental Neurophysiology, Plzeň

Laboratory of Experimental Neurophysiology, Plzeň We are Laboratory of Experimental Neurophysiology under Biomedical Center of the Faculty of Medicine in Pilsen. František Zitrický, M.D.

This page was created to share events and news from our lab. Tato stránka slouží pro sdílení novinek a událostí z naší laboratoře. Our goal is to understand mechanisms of memory processing on the level of brain neural networks. We focus on hippocampal circuits and their interactions with neocortical areas. Hippocampal system has been found crucial for declarative memory in humans and certain types of cognitive abilities in animals, namely for orientation and spatial memory. Because we can read the information code in hippocampal pyramidal cells relatively well, this system thus provides a fascinating field offering a direct insight into mechanisms of how brain represents external world and how this information is later recalled. The lab’s concept is to systematically explore properties of memory processing across networks within hippocampus and connected cortical areas. We mainly record electric activity from populations of place cells in laboratory rats and decode the neural information in high temporal resolution. This enables to study detailed kinetics of memory processing and to relate it with local brain oscillations and behavior. Members
Karel Ježek, M.D., Ph.D. – Research Group Leader
Karel Blahna, M.D., Ph.D. Lenka Sýkorová, M.Sc.
Štěpán Kápl, M.Sc. Zuzana Petránková, Ph.D., M.Sc. Michael Mareš
Kristýna Paulová
M.C.P. Stephanie Lissette Proskauer-Peña

02/11/2022

🧠 The webinar “The microbiome, immunity, and neurodevelopment trialogue: from womb to adulthood” recording is now available!

Watch and learn about the microbiome and its influence on immunity and the system from to adulthood.
👉 Find out more: https://loom.ly/6l9AE9U

09/03/2022
The Picower Institute's Biennial Spring Symposium, in conjunction with the JPB FoundationRegistration is free but requir...
05/05/2021

The Picower Institute's Biennial Spring Symposium, in conjunction with the JPB Foundation
Registration is free but required. Please click here to register.

The Picower Institute's Biennial Spring Symposium, in conjunction with the JPB Foundation

Neuroscientists discover a molecular mechanism that allows memories to form
09/10/2020

Neuroscientists discover a molecular mechanism that allows memories to form

When the brain forms a memory of a new experience, neurons called engram cells encode the details of the memory and are later reactivated whenever we recall it. A new MIT study reveals that this process is controlled by large-scale remodeling of cells' chromatin.

06/09/2019

Being Patient speaks to Dr. Dale Bredesen about

Navigating through odour world with grid cellshttps://www.cell.com/neuron/fulltext/S0896-6273(19)30297-1 #
26/04/2019

Navigating through odour world with grid cells
https://www.cell.com/neuron/fulltext/S0896-6273(19)30297-1 #

Grid cells in entorhinal cortex underlie spatial orientation and path finding. Bao et al. show that entorhinal grid-like codes with behavioral relevance emerge when humans mentally navigate an olfactory landscape, highlighting potential neural mechanisms for locating odor sources in odiferous envir...

Týden mozkuve Studijní a vědecké knihovně Plzeňského kraje, Vzdělávací centrum hlavní budovy SVK, Smetanovy sady 2, 301 ...
12/03/2019

Týden mozku
ve Studijní a vědecké knihovně Plzeňského kraje, Vzdělávací centrum hlavní budovy SVK, Smetanovy sady 2, 301 00 Plzeň

12. 3. 2019 od 16.00 do 19. 00 hod.

Přednášející:
vědečtí pracovníci a pedagogové z Lékařské fakulty v Plzni Univerzity Karlovy

Program:

Paměť, její mechanizmy a poruchy
Karel Ježek

Význam neurogeneze v dospělém mozku
Filip Tichánek

Biologické rytmy a světlo
Dana Jelínková

Neurotransplantační léčba onemocnění mozečku: naděje nebo slepá ulička?
Jan Cendelín

Spánek a paměť ve zdraví a nemoci
Karel Blahna

Přidružená přednáška akce Týden mozku AV ČR Přednášející: vědečtí pracovníci a pedagogové z Lékařské fakulty v Plzni Univerzity Karlovy Program: 1. Paměť, její mechanizmy a poruchy Karel Ježek 2. Význam neurogeneze v dospělém mozku Filip Tichánek 3. Biologické rytm...

Dear colleagues.I want to wish you a wonderful and peaceful holidays with your beloved ones.I chose this picture because...
24/12/2018

Dear colleagues.
I want to wish you a wonderful and peaceful holidays with your beloved ones.

I chose this picture because it was just a full ordinary moment from one of those gatherings at our Lab, and I thought about how many ordinary moments and people makes our lives special.

Please take a minute to look at the picture and just as the old renaissance paintings where it seems people is just living and enoying. (eg. Wedding at Cana from Paolo Veronese)

Thank you all for making my life full of small and ordinary moments!

Enjoy life and take happiness in the small moments.
SLPP

Adresa

Univerzita Karlova Lékařská Fakulta V Plzni Biomedicínské Centrum Alej Svobody 1655/76
Plzen
32300

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Our Story

Our goal is to understand mechanisms of memory processing on the level of brain neural networks. We focus on hippocampal circuits and their interactions with neocortical areas. Hippocampal system has been found crucial for declarative memory in humans and certain types of cognitive abilities in animals, namely for orientation and spatial memory. Because we can read the information code in hippocampal pyramidal cells relatively well, this system thus provides a fascinating field offering a direct insight into mechanisms of how brain represents external world and how this information is later recalled. The lab’s concept is to systematically explore properties of memory processing across networks within hippocampus and connected cortical areas. We mainly record electric activity from populations of place cells in laboratory rats and decode the neural information in high temporal resolution. This enables to study detailed kinetics of memory processing and to relate it with local brain oscillations and behavior. Members Karel Ježek, M.D., Ph.D. – Research Group Leader Karel Blahna, M.D., Ph.D. František Zitrický, M.D. Lenka Sýkorová, M.Sc. Štěpán Kápl, M.Sc. Zuzana Petránková, Ph.D., M.Sc. Michael Mareš Kristýna Paulová M.C.P. Stephanie Lissette Proskauer-Peña