24/02/2026
Today’s Question:
A 32-year-old woman comes to the office for a preemployment examination. The patient has had mild shortness of breath on exertion over the past year, which she attributes to deconditioning. Three months ago, an ophthalmologist treated her for anterior uveitis. The patient has no other medical conditions and takes no medications. She does not use to***co, alcohol, or recreational drugs. Blood pressure is 110/70, pulse is 72/min, and respirations are 14/min. On physical examination, visual acuity is within normal limits. There is swelling of the parotid glands and the lungs are clear to auscultation. Chest x-ray reveals enlarged hilar lymph nodes and nodular pulmonary infiltrates. Which of the following histopathological findings are most likely to be seen on lymph node biopsy in this patient?
A. Caseating epithelioid granulomas and acid-fast bacilli
B. Eosinophilic, perivascular, inflammatory infiltrate
C. Granulomatous inflammation with no central necrosis
D. Reed-Sternberg cells surrounded by inflammatory cells
E. Small basophilic cells with granular nuclear chromatin