Internal Medicine Update

Internal Medicine Update updates in internal medicine

06/09/2025

A longitudinal study found that high consumption of artificial sweeteners was linked to 62% faster cognitive decline in middle-aged and older adults - equivalent to 1.6 extra years of aging. The effect was strongest in people under 60 and those with diabetes, but wasn't seen in older adults. http://ms.spr.ly/6187s5Ygx

15/07/2025

The Patient Did Well — So the Insurance Company Won’t Pay
Dr. Paul Sax highlights the frustrations of peer-to-peer discussions with insurance companies. https://jwat.ch/4eRzVyc

21/11/2024

Metformin was associated with a lower rate of asthma attacks, with further reductions with the use of GLP-1RA. https://ja.ma/40OTLVZ

21/11/2024

Among hospitalized patients with cirrhosis and ascites, early diagnostic paracentesis within 12 to 24 hours was associated with lower in-hospital mortality, shorter hospital length of stay, and fewer acute kidney injuries. https://jwat.ch/4eD6n5B

10/11/2024

Unplanned pregnancies are still being reported among people using GLP-1 drugs, but now fertility specialists are incorporating the medicines into preconception care plans.

10/11/2024

In a meta-analysis that included over 3,700 patients with heart failure with preserved ejection fraction (HFpEF) and obesity, semaglutide lowered the rate of worsening HF events compared with placebo.

In a subgroup analysis, patients with body mass index ≥35 kg/m2 were more likely to benefit from semaglutide than those with lower body mass index. In patients with HFpEF and obesity, we suggest a GLP-1 receptor agonist and lifestyle interventions for weight loss rather than lifestyle interventions alone.

Stay with What's New in : https://ow.ly/n4Me50TYtOS

07/11/2024

In a placebo-controlled trial, frequency of nocturnal leg cramps was significantly lower with vitamin K2. https://jwat.ch/48zxNbq

07/11/2024

🚨 New Clinical Practice Update! 🚨

Our latest guidance provides new insights into when to use potassium-competitive acid blockers (P-CABs). Spoiler alert: P-CABs should not typically represent the first choice for treating all patients with heartburn or acid-related disorders at present.

Key takeaways:

🔹P-CABs should generally be used for the eradication of H. pylori infection and considered for the treatment of severe erosive esophagitis and for patients with GERD who fail twice-daily PPI therapy.

🔹P-CABs may be considered for other acid-related conditions if other treatments haven’t worked, but factors like dosage, availability, cost, and safety must be carefully evaluated.

Check out the full guidance: https://ow.ly/Qg7650U1t1A.

Watch authors Drs. Amit Patel and Loren Laine discuss the highlights: https://ow.ly/Cr2m50U1t1z.

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