Neonatal shortcuts

15/11/2025

Acidosis/Alkalosis and calcium homeostasis

15/11/2025

A review of normal calcium and phosphate homeostasis, including discussion of vitamin D metabolism and the actions of PTH, as well as brief mention of the ne...

14/11/2025

14/11/2025

Mechanisms underlying higher BP in infants with BPD

💥Hypoxia and hypercarbia increase systemic vascular resistance through stimulation of peripheral arterial chemoreceptors. The latter could cause catecholamine release and increased vasomotor tone

💥Inflammation causes abnormal collagen deposition and endothelial dysfunction via multiple pro-inflammatory cytokines, complementing the role of angiotensin II

14/11/2025

Purpose of review Bronchopulmonary dysplasia (BPD) remains a very common complication of extreme prematurity and has significant adverse long-term consequences. Specific treatments to prevent the development of BPD or to treat established BPD are very limited. We have reviewed recent advances in the...

13/11/2025

💥💥💥Neuromonitoring techniques in neonates with hypoxic ischemic encephalopathy

13/11/2025

💥Delaying the start of enteral feeding was previously thought to reduce the incidence of NEC; however, recent studies have shown that early initiation of enteral nutrition does not increase the incidence of NEC.

💥Breast milk is the only factor that has consistently been shown to improve NEC.

💥The incidence of NEC in formula-only fed infants is 6–10 times higher than that
in exclusively breastfed infants.

💥Recognized nutrients
aside, some non-nutrient components of breast milk contribute to gastrointestinal immune function and mucosal
integrity, including IgA, growth hormones (epidermal growth factor, insulin, and insulin-like growth factor), polyunsaturated fatty acids, and oligosaccharides.

13/11/2025

BiB trial 💥💥

This randomized clinical trial conducted at centers of the United States Neonatal Research Network assesses whether early intratracheal administration of a combination of budesonide mixed with surfactant, compared with surfactant alone, reduces physiologic bronchopulmonary dysplasia or death by 36.....

13/11/2025

Meta-analysis of budesonide and surfactant combination for the prevention of bronchopulmonary dysplasia in preterm neonates based on gestational age

BackgroundBudesonide, an inhaled corticosteroid, and surfactant, a substance that lowers surface tension in the lungs, are both used to prevent Bronchopulmon...