Intensive Care Medicine

Intensive Care Medicine The official page for ICM, Intensive Care Medicine.
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ICM is an international peer-reviewed medical journal intended for all those who are involved in intensive care medicine. ''Intensive Care Medicine'' is the publication platform for the communication and exchange of current work and ideas in intensive care medicine. The journal publishes original research papers, reviews, as well as discussions on technology, methods, new apparatus and modificatio

ns of standard techniques and correspondence concerning matters of topical interest or relating to published material. Official journal of The European Society of Intensive Care Medicine and The European Society of Paediatric and Neonatal Intensive Care.
12 issues per year.

https://zurl.co/hPEox Peripheral muscle ultrasound allows bedside assessment and serial monitoring of muscle mass and qu...
23/04/2026

https://zurl.co/hPEox Peripheral muscle ultrasound allows bedside assessment and serial monitoring of muscle mass and quality in critically ill patients, including sedated or mechanically ventilated patients. Current evidence remains limited and heterogeneous, with variability in protocols, measurement indices, and reliability. Routine ICU adoption depends on standardised acquisition, validated parameters, and defined training requirements.

https://zurl.co/QFjEd Right ventricular injury in moderate–severe ARDS is associated with increased mortality. Ventilati...
23/04/2026

https://zurl.co/QFjEd Right ventricular injury in moderate–severe ARDS is associated with increased mortality. Ventilation must limit tidal increases in right ventricular afterload while maintaining gas exchange and oxygen delivery. PEEP, driving pressure, respiratory rate and hypercapnia require careful balance, and prone positioning can support both lung and right ventricular protection.

https://zurl.co/s8UAO A prospective cohort included 444 adults with community-onset sepsis enrolled within 6 hours of em...
22/04/2026

https://zurl.co/s8UAO A prospective cohort included 444 adults with community-onset sepsis enrolled within 6 hours of emergency department arrival. Blood and urine biomarkers were grouped into host resistance, disease tolerance, and damage signatures. Greater damage was associated with higher 90-day mortality, while differences across sepsis subtypes were most pronounced for disease tolerance and damage.

https://zurl.co/aFN1X  -Quizz   Peripheral VA-ECMO may create two distinct circulations, with the mixing point determini...
22/04/2026

https://zurl.co/aFN1X -Quizz Peripheral VA-ECMO may create two distinct circulations, with the mixing point determining which blood reaches the cerebral circulation. Hypercapnic blood reaching the supra-aortic vessels can trigger central chemoreceptors and cause intense tachypnoea and dyspnoea despite preserved oxygenation and normal lung imaging. Increasing sweep gas flow enhances extracorporeal CO₂ removal and rapidly relieves symptoms.

https://zurl.co/iy82v  -Quizz   A patient supported with peripheral VA-ECO without venting develops severe dyspnea and t...
21/04/2026

https://zurl.co/iy82v -Quizz A patient supported with peripheral VA-ECO without venting develops severe dyspnea and tachypnea despite normal lung imaging and preserved oxygenation. Right radial arterial blood gases show respiratory alkalosis, while post-oxygenator blood gases reveal hypercapnia. What is the most likely mechanism?

https://zurl.co/q9VP5 Randomized trials of adequate power have not compared corticosteroids with placebo in severe influ...
21/04/2026

https://zurl.co/q9VP5 Randomized trials of adequate power have not compared corticosteroids with placebo in severe influenza pneumonia. Cohort studies and meta-analyses remain limited by bias and low certainty. Ongoing randomized trials are expected to clarify the benefit-risk ratio, and corticosteroids should not be used for influenza treatment until these trials are completed.

https://zurl.co/tio9U Post-intensive care syndrome affects physical, cognitive, psychological and social recovery after ...
20/04/2026

https://zurl.co/tio9U Post-intensive care syndrome affects physical, cognitive, psychological and social recovery after critical illness. Multidisciplinary follow-up has improved recognition of long-term needs but often remains disconnected from primary care and specialist care. A transdisciplinary approach is proposed to support more coordinated post-ICU care.

https://zurl.co/qooVG   In critically ill adults undergoing rapid sequence intubation, ketamine was associated with a hi...
20/04/2026

https://zurl.co/qooVG In critically ill adults undergoing rapid sequence intubation, ketamine was associated with a higher lowest mean arterial pressure in the first 10 minutes than propofol. The mean arterial pressure difference was not sustained over the first hour, and severe hypotension rates were similar. Cardiovascular collapse was less frequent with ketamine, while mortality was numerically higher at day 7, in the ICU and in hospital.

https://zurl.co/PVIbg  -Quizz   A 64-year-old woman with diabetes and rheumatoid arthritis developed life-threatening se...
19/04/2026

https://zurl.co/PVIbg -Quizz A 64-year-old woman with diabetes and rheumatoid arthritis developed life-threatening sepsis from Staphylococcus aureus sternoclavicular joint infection complicated by thoracocervical necrotising soft tissue infection. Early surgical debridement, articular lavage, and intravenous antibiotics were the treatment cornerstone, while MRI, HBOT, and other measures were not recommended if they risked delaying urgent surgical exploration.

 -Quizz   A 64-year-old woman with rheumatoid arthritis on prednisone and type 2 diabetes on insulin was transferred to ...
19/04/2026

-Quizz A 64-year-old woman with rheumatoid arthritis on prednisone and type 2 diabetes on insulin was transferred to intensive care with high fever and sepsis-induced multiple organ dysfunction after 2 weeks of right sternoclavicular joint pain. CT showed emphysematous osteomyelitis, necrotizing soft tissue infection, emphysematous cystitis, and gas in the iliac veins and pelvic floor tissues. What are the key management steps in the early phase?

https://zurl.co/U0RBi An international consensus proposes bedside criteria for refractory septic shock, including persis...
18/04/2026

https://zurl.co/U0RBi An international consensus proposes bedside criteria for refractory septic shock, including persistent hyperlactatemia or prolonged capillary refill time, fluid unresponsiveness, high vasopressor needs and ultrasound assessment. The framework offers a common language for severe septic shock, but no minimum shock duration or specific lactate threshold was agreed. External validation is still needed.

https://zurl.co/BuFV5 A five-round Delphi process with 56 expert panellists reached consensus on clinical criteria for r...
18/04/2026

https://zurl.co/BuFV5 A five-round Delphi process with 56 expert panellists reached consensus on clinical criteria for refractory septic shock. Persistently elevated lactate and/or prolonged capillary refill time were retained in patients with septic shock who are fluid unresponsive and require norepinephrine base equivalent doses above 0.5 µg/kg/min. Critical care ultrasonography was retained to assess alternative causes of shock.

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