24/04/2026
Experiencing intense itching after stopping antihistamines? You’re not alone.
Long-term use of cetirizine or levocetirizine has been linked to rebound itching (pruritus) after discontinuation — even in patients who didn’t previously have itch symptoms.
This reaction can occur within days of stopping and, in some cases, may be severe enough to require medical support.
Understanding this effect is key to managing symptoms safely. If you’re considering stopping antihistamines, seek professional advice to reduce the risk of rebound reactions.
Read more: https://www.skincarenetwork.co.uk/dermatology-news/antihistamine-withdrawal-itch-understanding-rebound-pruritus-after-long-term-cetirizine-or-levocetirizine-use/