Cell Guidance Systems

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Cell Guidance Systems

Cell Guidance Systems provides innovative life science research tools and services.

Cell Guidance Systems is a regenerative medicine company providing reagents and services for cell based research and developing protein therapeutics using its PODS platform.

09/02/2026

Advancing EV Research with Tangential Flow Filtration

Tangential Flow Filtration is changing how researchers isolate and process extracellular vesicles. It offers a scalable, reproducible alternative to ultracentrifugation while helping preserve EV integrity.

In our latest blog, we cover:
• Higher throughput with reduced membrane fouling
• Gentle processing conditions to maintain EV quality
• Scalable workflows for concentration and diafiltration
If you are working in EV research, this is a method worth exploring.

Read more here: https://lnkd.in/eaiHVHZy

02/02/2026

Embryo implantation is a finely choreographed event in which extracellular vesicles have a key role. Learn more in our weekly blog

https://lnkd.in/e6pwfkan

26/01/2026

Why is the brain one of the softest tissues in the human body?

This week, our blog explores how the brain’s extreme softness (≈0.5–1 kPa) makes it behave more like a hydrogel than a fibrous tissue.

How does it achieve this level of softness and why?

https://lnkd.in/eM6UgAHH

19/01/2026

Our latest blog post “Cytokines and growth factors: what are International Units?” breaks down why International Units (IU) are sometimes used to express biological activity and why that distinction matters:
• Why IU measure biological potency, not quantity.
• How IU are defined against global reference standards like WHO assays.
• Why IU values vary between labs and why not all growth factors have IU standards.
• Practical tips on interpreting specific activity (IU/mg) when planning experiments.

Read the full article: https://lnkd.in/e7XGZibP

22/12/2025

EVs: complex cellular communication

Compared to simple cytokines, extracellular vesicles are very complex means of cellular communication. This complexity and ability to deliver multiple "notes" at the same time may make EVs difficult to decipher, but also holds the promise of far more powerful therapeutic composition.

https://lnkd.in/eMR8iZ-B

15/12/2025

Creating robust chemokine gradients to create cellular niches is simple with PODS sustained release chemokines.

Read more in our weekly blog

https://lnkd.in/eJWvY4sq

08/12/2025

Not so rare

Rare diseases are so numerous that they are collectively very common. The prospects for people with rare diseases are improving as most diseases are genetic and the tools to identify and correct these errors are improving.

Read more

https://lnkd.in/eGYfwjU3

01/12/2025

Exosomes in 2026: hype and potential

Over the last few years, exosomes have increasingly been promoted for their cosmetic benefits. The risk is that poor quality data from cosmetics impacts efforts to develop EVs with clinical benefits, particularly for wound healing applications.

Read more in our blog

https://lnkd.in/eYzbJhPv

24/11/2025

The Hunters gene therapy breakthrough announced today highlights the important role of medical charities in funding clinical research for drugs that would not be commercially viable.

Read the full blog:

https://lnkd.in/ex2zZUdc

27/10/2025

A novel “shaking sensor” has been developed that enables real-time monitoring of cytokines – paving the way for continuous inflammation tracking and insights into acute and chronic disease management.

Read more:

https://www.cellgs.com/blog/how-does-a-shaking-sensor-provide-real-time-cytokine-monitoring.html

13/10/2025

How Many More Immune Cells Remain to Be Identified?

With the awarding of a Nobel Prize for the discovery of regulatory T cells, we ask how many immune cells remain to be identified. This isn’t just academic; each newly discovered cell could reshape how we understand immunity, disease, and therapeutics.

Read more here:

https://lnkd.in/e_mJ4t7g

06/10/2025

Losing retinal ganglion cells (RGCs) has long meant irreversible vision loss — but that may be changing.

Researchers using PODS® micro-cages (Polyhedrin Delivery System) loaded with growth factors (BDNF + GDNF) have shown dramatic improvements in RGC survival and regeneration — both in vitro and in vivo.

✅ 15× higher survival of transplanted human RGCs
✅ Neuroprotective effects for host retinal cells
✅ Sustained, localized growth factor release

This could shift eye-repair strategies from simple replacement to “support + replace.”

Read more in Cell Guidance Systems’ latest post:
https://lnkd.in/eD5j32Ka

Address

Maia Building, Babraham Research Campus
Cambridge
CB223AT

Website

https://www.cellgs.com/mc-pods-home.htm?E2EPv=1

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