Cell Guidance Systems

Home
United Kingdom
Cambridge
Cell Guidance Systems

Cell Guidance Systems provides innovative life science research tools and services.

Cell Guidance Systems is a regenerative medicine company providing reagents and services for cell based research and developing protein therapeutics using its PODS platform.

27/10/2025

A novel “shaking sensor” has been developed that enables real-time monitoring of cytokines – paving the way for continuous inflammation tracking and insights into acute and chronic disease management.

Read more:

https://www.cellgs.com/blog/how-does-a-shaking-sensor-provide-real-time-cytokine-monitoring.html

13/10/2025

How Many More Immune Cells Remain to Be Identified?

With the awarding of a Nobel Prize for the discovery of regulatory T cells, we ask how many immune cells remain to be identified. This isn’t just academic; each newly discovered cell could reshape how we understand immunity, disease, and therapeutics.

Read more here:

https://lnkd.in/e_mJ4t7g

06/10/2025

Losing retinal ganglion cells (RGCs) has long meant irreversible vision loss — but that may be changing.

Researchers using PODS® micro-cages (Polyhedrin Delivery System) loaded with growth factors (BDNF + GDNF) have shown dramatic improvements in RGC survival and regeneration — both in vitro and in vivo.

✅ 15× higher survival of transplanted human RGCs
✅ Neuroprotective effects for host retinal cells
✅ Sustained, localized growth factor release

This could shift eye-repair strategies from simple replacement to “support + replace.”

Read more in Cell Guidance Systems’ latest post:
https://lnkd.in/eD5j32Ka

29/09/2025

Under pressure: Modeling glaucoma using sustained cytokine release PODS

Researchers have engineered an in vitro model of the trabecular meshwork (TM) mimicking chronic disease by combining biomimetic collagen scaffolds with PODS® microcrystals that gradually release TGF-β2 .

👉 Check it out:

https://lnkd.in/eGKB9Ur7

22/09/2025

Climate change 🌍 not just rising seas: It may also reshape our biology.

Our latest blog explores how heat, pollution, and disrupted light cycles can damage DNA, alter gene expression, and potentially increase cancer risk. Vulnerable populations may face the greatest impact, making this a critical public health issue.

Read the full article

https://lnkd.in/ep3-aKJx

15/09/2025

Can there be any science without standards?

Setting Standards: Making Research Scientific

Advancing science isn’t just about new discoveries. It’s about how we measure, compare, and agree.

https://lnkd.in/eJb5JgM2

08/09/2025

New on the CellGS Blog: What Are the Most Effective Ways to Concentrate EVs?

EVs often need to be concentrated before purification and downstream analysis. This can be tricky, especially when working with large sample volumes and aiming to preserve both purity and bioactivity. We break down all the options with a clear, method-by-method guide.

https://lnkd.in/e5pY-7mA

18/08/2025

Could Natural Killer (NK) cell-derived extracellular vesicles (EVs) revolutionise how we fight cancer?

While NK cells are powerful cancer killers, direct cell therapy faces hurdles such as poor tumour infiltration, short survival times and immunogenicity. NK-EVs: are nano-sized vesicles (30-150 nm) that carry a cancer-fighting arsenal derived from their parent cells but with some distinct advantages:

✅ Enhanced tumour pe*******on due to small size
✅ Non-immunogenic and inherently safe and scalable manufacture
✅ Can be engineered to carry additional therapeutic cargo

Recent NK-EV studies show promising anti-tumour activity across breast, colon, ovarian, and brain cancers. IL-15-treated NK-EVs demonstrated enhanced cytotoxic effects against glioblastoma and other aggressive cancers.

This positions NK-EVs as potentially transformative for solid tumours, traditionally challenging for immunotherapy. While challenges remain in large-scale production and standardisation, the potential to combine NK-EVs with existing immunotherapies such as checkpoint inhibitors opens fascinating possibilities.

Read the article https://lnkd.in/eNdDNEXC

11/08/2025

Do exosomes work as cosmetic ingredients?

Cosmetic products containing exosomes are now widely available. In our weekly blog, we look at the rapidly growing exosome cosmetics market and explore the evidence for their cosmetic effect.

https://lnkd.in/eDz-QtvF

21/07/2025

🧬 What are SASP “biological-clock” proteins and why do they matter?
We just published a new blog post exploring the role of SASP proteins, which are secreted by senescent cells and act as biological timekeepers within the body.

These proteins are a key part of how aging cells influence their environment—sometimes helping with tissue repair, but also contributing to chronic inflammation and age-related diseases when left unchecked.

If you're interested in aging biology, biomarkers, or next-gen therapies, this is a quick and insightful read.

👉 Read the article
https://lnkd.in/eEb5BryY

Address

Maia Building, Babraham Research Campus
Cambridge
CB223AT

Website

https://www.cellgs.com/mc-pods-home.htm?E2EPv=1

Alerts

Be the first to know and let us send you an email when Cell Guidance Systems posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Shortcuts

Want your practice to be the top-listed Clinic in Cambridge?