12/11/2025
📢New research!!
Generation Scotland volunteers have contributed to a methylome-wide association study examining DNA methylation associated with major depression. This meta-analysis is the largest to date and included 18 studies with over 24,000 participants. The results reveal that depression has distinct biological signatures in the blood, particularly in genes that control immune function, inflammation and metabolism.
Read the full paper, Shen et al. 2025: https://www.nature.com/articles/s44220-025-00486-4