22/06/2021
Did You know Hyperbaric Oxygen Therapy can help with bone health and healing?
Non-union/Non healing bones
& the Benefits of HBOT
Bone Healing can be delayed or stopped altogether by extensive trauma, bone loss, infection, ageing, premature mobilization, diabetes and osteonecrosis (a disease caused by reduced blood flow to bones in the joints, leading to bone death and breakdown). To read more.
Young athletes as well as elderly diabetics can have non-union or non-healing fractures. These factors can cause chronic pain and disability for patients. In these circumstances, re-establishing the structural integrity of the bones can be a major challenge for doctors.
Oxygen is an essential material for cell metabolism, and reparative processes. Cell proliferation and collagen synthesis have an especially increased demand for oxygen. Evidence from animal and cell line studies has shown that HBOT, the administration of pure oxygen at pressures greater than 1 ATA, results in increased growth factor production. (1)
HBOT is known to stimulate the production of collagen, a tough, fibrous material that fills the space between broken bones and helps ‘knit’ them back together. Hyperbaric oxygen also promotes fast growth of new capillaries in affected areas, which in turn brings more oxygen and nutrients to the bones.
In particular, additional hyperbaric oxygen increases production of osteoblasts and osteoclasts, the cells vital for bone growth, healing and the removal of old, dead bone. Numerous animal studies have demonstrated that osteoblasts and osteoclasts are exquisitely reactive to increased oxygen. In 2007, D. Wu et al conducted an experiment for Connective Tissue Research , investigating in vitro the effects of hyperbaric oxygen on osteoblasts, the cells responsible for synthesizing bone. They observed that HBOT stimulated proliferation of osteoblasts, providing direct cellular evidence that HBOT is effective for fracture healing and bone growth.