Defying Dementia

Defying Dementia Defying Dementia - Raising funds and awareness of the research taking place at Lancaster University into Alzheimer's and neurodegenerative brain disease.

Several years ago we developed a drug that blocks the formation of 'senile plaques' found in the brains of victims of Alzheimer's disease/dementia. This drug blocks the assembly of these plaques, along with their toxic effect, on brain cells. It is highly stable in the body and is tagged so it can cross the blood-brain barrier. The drug reduces the load of plaques present in cell models of the disease, along with reducing inflammation and oxidative damage. Lancaster University was granted a patent for this technology, however the underlying lab work has reached the end of funding by Research Councils. Unfortunately, the drug does not yet have the high technology readiness level and low perceived risk demanded by the pharmaceutical industry. Therefore, we are launching a crowd-funding campaign to raise money which will re-invigorate the stalled technology and ultimately get the drug into human clinical trials! This page has been created to promote our campaign and raise awareness of the research taking place at Lancaster University, so please 'like' us to be kept updated with our progress!

We're pleased to announce another Defying Dementia open day on December 3rd (1.30 pm - 4.30 pm) to be held in Furness Le...
11/11/2025

We're pleased to announce another Defying Dementia open day on December 3rd (1.30 pm - 4.30 pm) to be held in Furness Lecture Theatre 3 on our Bailrigg campus. We will have three presentations by our current researchers and a tour of the Defying Dementia labs. Please do sign up and support us at:

https://www.eventbrite.com/e/defying-dementia-open-day-tickets-1850432727099?aff=oddtdtcreator

If you need any help finding your way there please feel free to contact me directly on e.parkin@lancaster.ac.uk

Please do come along and find out more about our dementia research funded directly by your great efforts. Thanks again for your support and I hope to see you there.

Dr. Edward Parkin (scientific lead for DD)

Defying Dementia Open Day

This week, we were absolutely delighted to celebrate our Defying Dementia charity shop raising over an incredible £100,0...
22/08/2025

This week, we were absolutely delighted to celebrate our Defying Dementia charity shop raising over an incredible £100,000 for Dementia research!! Every penny raised by the charity shop has gone straight to the Defying Dementia team’s research into creating a drug effective against Alzheimer’s disease.

We would like to thank Linda and Neil Warrington for bringing to life the charity shop and making it the huge success that it is today, as well as all of the volunteers who give up their time in the shop, our supporters who donate their items and the community who continue to shop in the charity shop. Your support means that our Defying Dementia can continue their vital research into Alzheimer’s disease and the cause and effects of Dementia, so THANK YOU 💛🖤

Address

Philanthropy, Alumni & Supporter Engagement, C Floor, University House
Lancaster
LA14YW

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm

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