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T-Nutrition, 33-35 Victoria Street, Liverpool (2025)

17/11/2025

🧪 Ingredient Spotlight: Rutaecarpine

Source: A bioactive alkaloid extracted from the Evodia rutaecarpa fruit, traditionally used in Eastern herbal medicine for energy, circulation, and metabolic support.

🔑 Key Benefits

Enhances caffeine metabolism

Supports CYP1A2 enzyme activity

Reduces caffeine related jitters

Promotes smoother, cleaner energy

Helps prevent late day caffeine disruption

Supports overall metabolic clearance

🧬 What Is Rutaecarpine?
Rutaecarpine is a naturally occurring alkaloid that has a unique effect on how the body processes stimulants. Its main action is increasing the activity of CYP1A2, the primary liver enzyme responsible for breaking down caffeine. This makes it one of the few ingredients that can actively accelerate caffeine clearance.

⚙️ How It Works
Rutaecarpine activates CYP1A2 through two key mechanisms:
1️⃣ Upregulation of CYP1A2 expression, increasing the amount of enzyme available.
2️⃣ Activation of existing CYP1A2 enzymes, making them work faster.

The result?
✔ Cleaner stimulant effects
✔ Reduced jitteriness
✔ Less caffeine hangover
✔ Faster return to baseline
✔ Improved sleep

Commonly used in sleep & relaxation formulas to speed up caffeine metabolism.

📏 Optimal Dosage
Effective dosing ranges from 50-100mg daily.
Best taken in the evening, or any time of the day to accelerate caffeine clearance.

💪🔵⚪💯

potlight

13/11/2025

Clarifying one point from the Lipidmax spotlight:

The well known Vitamin C and Lysine combination popularised by Linus Pauling is officially referred to as “Pauling Therapy”.

Different sources use different names, like “Pauling Protocol” and “Pauling Method”, but this is the clearest and most widely recognised term, so I’ll be using it consistently moving forward.

I’ve added a screenshot to show the mechanism in the video for anyone who wants to understand why these two ingredients are paired together.

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11/11/2025

🧪 Product Spotlight: LipidMax
Brand: Strom Sports
Flavour: Mango
Serving Size: 1 scoop (10 g)
Servings Per Tub: 40

🔑 Key Benefits
Supports healthy cholesterol and lipid metabolism
Antioxidant and vascular support
High strength Vitamin C + Lysine combination
Includes Bergamot, Grapeseed and CoQ10
Designed for daily cardiovascular and metabolic support

🧬 What Is LipidMax?
LipidMax is Strom’s high strength lipid support formula built for anyone who wants to take a nutritional approach to maintaining cholesterol balance and overall cardiovascular wellness. It uses the famous Linus Pauling inspired combo of high dose Vitamin C and Lysine, a pairing historically linked with vascular health and connective tissue integrity. Strom then adds Citrus Bergamot, Grapeseed Extract and CoQ10 to create one of the most comprehensive daily wellness stacks in the UK supplement space. No medical claims here, just a serious, intelligently dosed formula for those who want to support their health through consistent, well chosen nutrition.

⚙️ Ingredient Breakdown
Vitamin C (1000 mg): Antioxidant support, collagen formation and circulatory wellbeing.
L-Lysine (5000 mg): Essential amino acid linked to tissue integrity and vascular structure.
Citrus Bergamot (500 mg): Popular for supporting healthy cholesterol ratios.
Grapeseed Extract (500 mg): Polyphenols that support blood flow and oxidative balance.
CoQ10 (250 mg): Supports natural mitochondrial energy production and cardiovascular wellness.

🧩 How LipidMax Works
Vitamin C and Lysine support collagen, stability and circulatory wellness. Bergamot and Grapeseed help maintain healthy lipid balance and antioxidant status. CoQ10 supports cellular energy and vitality. Together they form a daily use nutritional formula ideal for anyone focused on long term health support.

📏 How to Use
1 scoop daily mixed with 400-500ml water

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10/11/2025

🧪 Ingredient Spotlight: L-Citrulline

Source: A non-proteinogenic amino acid naturally found in watermelon, cucumber, courgette, and other gourds. Dietary amounts are far too low for performance benefits, so most supplement forms use purified synthetic L-Citrulline for stability, accuracy, and consistent dosing.

🔑 Key Benefits

Boosts nitric oxide (NO)

Enhances blood flow, pumps, and vascularity

Improves endurance and training output

Supports nutrient delivery to working muscles

Reduces fatigue via improved ammonia clearance

Outperforms L-Arginine for raising NO levels

🧬 What Is It?
L-Citrulline is converted into L-Arginine, which the body then converts into nitric oxide, the key molecule responsible for vasodilation.

Unlike L-Arginine itself, citrulline easily survives digestion, absorbs efficiently, and raises plasma arginine levels more effectively.

This leads to stronger pumps, better circulation, and improved performance during high-intensity or high-volume training.

⚙️ Why Not L-Arginine?
Oral L-Arginine suffers from poor absorption, intestinal breakdown, and heavy first-pass metabolism.

L-Citrulline bypasses these issues, providing a cleaner and more reliable pathway to nitric oxide production.

This is why modern pre-workouts rely on citrulline as their primary pump ingredient.

⚙️ Citrulline vs Citrulline Malate
Pure L-Citrulline:

Highest citrulline content

Strongest for pumps & blood flow

Precise dosing (ideal for 6-8g protocols)

Citrulline Malate (CM):

L-Citrulline bound to Malic Acid

Malate may support ATP production

Common in pre-workouts for added endurance

Standard ratio is 2:1 (meaning 6g CM = ~4g real citrulline)

Both work, but pure citrulline produces the most reliable NO response.

📏 Optimal Dosage
Effective: 4g
Optimal: 6-8g
Some advanced formulas use 10g+ pure citrulline for maximal pumps and endurance.

For 2:1 Citrulline Malate:
8g CM = ~5.3g citrulline
6g CM = ~4g citrulline

Aim for the actual citrulline content, not just the total grams on the label.

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06/11/2025

TASTE TEST: Applied Nutrition’s brand new Critical Whey… Chiquita Banana Strawberry Smoothie flavour.

I expected a standard strawberry & banana milkshake vibe… but this actually tastes like a fresh fruit smoothie blended with vanilla ice cream.

Much cleaner, brighter and more natural tasting than classic whey flavours.

The new Critical Whey formula now uses milk protein concentrate alongside WPC, WPI and hydrolysed whey, giving it a richer, smoother texture with a natural sweetness.

✅ 24g protein per serving
✅ Same potassium as one whole banana
✅ Informed Protein tested
✅ Chiquita-branded collab flavour
✅ Great mixability: thicker, creamier texture

If you want a protein that actually tastes like a real smoothie, not a milkshake… this one surprised me in the best way. 🍌🍓🔥

Let me know in the comments if you've tried this flavour of Critical Whey yet! 💪😎👍

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04/11/2025

🧪 Ingredient Spotlight: PeptiStrong™
Source: A clinically engineered fava bean (Vicia faba) protein hydrolysate delivering targeted peptides that enhance strength, recovery, and anabolic signalling.

🔑 Key Benefits

Supports muscle growth and strength

Reduces muscle protein breakdown (anti-catabolic)

Enhances recovery after high-intensity training

Improves anabolic signalling through the mTOR pathway

Helps maintain lean mass during dieting

Supports performance in both resistance and endurance athletes

🧬 What Is PeptiStrong™?

PeptiStrong™ is a patented fava-bean-derived protein hydrolysate created by Nuritas using AI peptide discovery. It delivers bioactive peptide fractions (including NPN_1 and NPN_2) that interact directly with key muscle pathways.

Unlike regular protein, these peptides target specific molecular switches responsible for muscle preservation, growth, and recovery.

It’s vegan, non GMO, highly digestible, and clinically studied for functional performance.

⚙️ How It Works

PeptiStrong™ supports performance and recovery through three main mechanisms:

1️⃣ Anti-Catabolic Action
Reduces muscle protein breakdown by regulating genes linked to proteolysis, helping you stay anabolic, even under stress, dieting, or high volume training.

2️⃣ mTOR Activation
Promotes anabolic signalling to support muscle growth, repair, and strength development.

3️⃣ Recovery & Fatigue Reduction
Improves muscle regeneration markers and reduces exercise induced inflammation, helping you bounce back faster between sessions.

📏 Optimal Dosage

Clinical data supports:
✅ 2.4g daily (standard effective dose)
✅ Can be taken pre or post workout (or with a meal)
✅ Stacks perfectly with protein and creatine
✅ Ideal for cutting phases, fasted training, high volume, and anyone needing stronger recovery support

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03/11/2025

DIM: The Truth Behind This ‘Test Booster’ Ingredient 👀

🧬 What DIM Actually Does

DIM shows up in a lot of testosterone boosters and hormone support formulas, but most people don’t understand what it really is, or how it actually works.

DIM starts as Indole-3-Carbinol, a natural compound found in cruciferous vegetables like broccoli and kale.

Your stomach converts I3C → DIM during digestion… but the amount you’d get from food alone is tiny, that’s why most people supplement it directly.

So what does it do?
✅ DIM is not an aromatase inhibitor
✅ It doesn’t block estrogen
✅ It doesn’t crash estrogen

What it does is shift estrogen metabolism toward the clean 2-hydroxyestrone (2-OHE1) pathway, and away from the 16α-hydroxyestrone (16α-OHE1) pathway, which is linked to mood swings, fluid retention, and estrogen dominant symptoms.

In a nutshell; You can feel more androgen dominant, without actually crashing your estrogen.

Typical doses: 100-200mg per day.
More is not better.

For quality formulas containing DIM, the OG DNA Sports Man Up and Applied Nutrition Test X remain the solid choices.

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30/10/2025

NMN Absorption Explained in 60 Seconds 🔬⚡

🧬 Does NMN actually get absorbed, or does it have to convert into NR first? 👀

Most people believe NMN can’t enter human cells at all… but the real story is far more interesting.

Here’s the quick breakdown:

✅ Normal pathway: NMN is usually dephosphorylated into NR → transported into the cell → rebuilt into NAD⁺.

✅ But… animal studies and cell models suggest a gut transporter called Slc12a8 may absorb NMN directly.

✅ The catch: that transporter is confirmed in mice, but human activity is still unclear.

So the most accurate answer right now?

NMN likely works through a combination of NR conversion and possible direct uptake.

That’s why some people (like myself) feel NMN working almost immediately

If you want more breakdowns like this, let me know what to cover next. ⚔️⚡ Mark

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28/10/2025

HR Labs have switched two of the most important mood and focus ingredients in the latest Limited Edition Defib flavours:

✅ Rhodioprime → Salidropure
✅ 5% L-DOPA Mucuna → Generic Mucuna (Unspecified L-DOPA)

And here’s why that matters.

Rhodioprime6X blends salidroside + rosavins, giving you a calmer, smoother, serotonin leaning lift.

That’s why the original Defib paired it with high L-DOPA, to pull the experience back toward clean dopamine drive.

Salidropure, however, is pure salidroside:

• faster acting
• more dopaminergic
• more urgency + clean drive
• less need for L-DOPA support

In simple terms:

🔥 LIMITED EDITION = Sharper Focus + Urgency
🔥 ORIGINAL DEFIB = Smooth Energy & Mood Elevation

Let me know which version you prefer: clean urgency or mood elevation? 👇⚡️

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27/10/2025

🧪 Ingredient Spotlight: Pine Bark Extract

Source: Derived from the bark of the maritime pine tree (Pinus pinaster), this potent natural antioxidant has become a cornerstone of cardiovascular and organ support formulas.

🔑 Key Benefits

Enhances blood flow and circulation through natural nitric oxide activation

Protects the liver and cardiovascular system from oxidative damage

Reduces inflammation and supports vascular integrity

Aids recovery from high stress or on cycle conditions

Promotes healthy endothelial function and micro circulation

Works synergistically with taurine, N-acetyl cysteine, and other antioxidants

🧬 What Is Pine Bark Extract?
Pine Bark Extract is rich in proanthocyanidins: plant compounds with strong antioxidant and vasodilatory properties. By protecting blood vessels from free radical stress and improving nitric oxide signalling, it helps maintain smooth circulation and healthy organ perfusion. This is why you’ll often see it featured in On Cycle Support, Liver Health, and Heart Support products.

⚙️ How It Works
The bioactives in pine bark improve endothelial function, so the ability of your blood vessels to relax and deliver oxygen efficiently. They also help recycle vitamin C and enhance the body’s own antioxidant defence network (SOD and glutathione), lowering overall oxidative load.
Better circulation means better nutrient delivery, faster detoxification, and more efficient recovery.

📏 Dosage & Pycnogenol®
Typical generic extracts are standardised to 95 % proanthocyanidins, effective in the 100-200 mg daily range.

Pycnogenol® is a patented, clinically studied form of French maritime pine bark. It’s standardised for consistent potency and supported by extensive human trials showing benefits for vascular health, glucose balance, and nitric oxide output.

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20/10/2025

🧪 Ingredient Spotlight: Citrus Bergamot

Source: A potent extract from the Citrus bergamia fruit native to Calabria, Italy. Rich in unique polyphenolic compounds (neoeriocitrin, naringin, brutieridin, and melitidin), Citrus Bergamot is one of nature’s most powerful tools for maintaining cardiovascular and metabolic health.

🔑 Key Benefits

Helps lower LDL (“bad”) cholesterol and raise HDL (“good”) cholesterol

Supports healthy triglyceride levels and overall lipid balance

Enhances liver function and promotes detoxification of excess fats

Provides antioxidant and anti-inflammatory support for cardiovascular health

Aids immune regulation by reducing oxidative stress burden

Backed by human clinical studies showing improved cholesterol ratios

🧬 What Is Citrus Bergamot?

Citrus Bergamot extract (often standardised to 40% polyphenols) is a natural complex of flavonoids that mimic the beneficial effects of statins, without suppressing the body’s own cholesterol production pathways. It works by modulating HMG-CoA reductase and AMPK activation, the same energy-regulating enzyme targeted by exercise and fasting.

⚙️ How It Works

Bergamot’s polyphenols activate AMPK, helping the body shift from fat storage toward fat utilisation. This enhances glucose and lipid metabolism, supports arterial flexibility, and improves HDL function, crucial for clearing cholesterol from blood vessel walls. Its antioxidant actions also protect immune cells and reduce systemic inflammation linked to metabolic stress.

📏 Optimal Dosage

Clinical research supports 500-1000mg daily, taken with food. Standardised extracts (38-47% total flavonoids) provide the most consistent benefits for cholesterol, triglycerides, and inflammatory markers.

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13/10/2025

🧪 Ingredient Spotlight: CHOfactor™

Source: An advanced cognitive matrix combining key cholinergic compounds designed to enhance mental clarity, focus, and mind-muscle connection during training.

🔑 Key Benefits

Enhances cognitive performance and sustained focus

Boosts acetylcholine synthesis for sharper neural drive

Supports the brain under physical and psychological stress

Combats mental fatigue during prolonged or intense sessions

Works synergistically with stimulants for clean, sustained energy

Improves reaction time, coordination, and motivation

🧬 What Is CHOfactor™?

CHOfactor™ is a precision engineered blend combining Alpha GPC, Citicoline, and Huperzine A, three clinically supported nootropics known to strengthen the cholinergic system. Together, they elevate acetylcholine levels, the key neurotransmitter responsible for muscle activation, focus, and memory formation.

This makes CHOfactor™ especially effective in performance formulas where both the body and mind are pushed to their limits.

⚙️ How It Works

Alpha GPC delivers a high yield source of choline to fuel neurotransmitter production.

Citicoline (CDP Choline) enhances phospholipid synthesis and cognitive resilience.

Huperzine A inhibits acetylcholinesterase, extending acetylcholine activity and keeping you mentally locked in.

This tri-layer synergy sharpens the link between thought and movement, helping you sustain focus, power, and precision when it matters most.

📏 Dosage & Use

Typical inclusion ranges between 500-1000mg per serving when part of a full pre workout or focus matrix. Works best when used consistently alongside other performance compounds such as L-Tyrosine, Caffeine, or AmentoPump®.

💪🔵⚪💯

T-Nutrition

17/11/2025

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