SCE dermatology

SCE dermatology updated dermatological information is continuously posted in this page.

30/12/2025

A 6-year-old child is brought in with a round, itchy rash around the mouth that has slowly grown larger over the past week. The area is red with a raised scaly border and a lighter center. The parent reports the child recently started wrestling at school and has been sharing sports equipment.

No fever. No pain. Just persistent itching that isn’t improving with regular moisturizer.

What’s the diagnosis?
Drop your answer below

This is for educational purposes only

30/12/2025

A 4-day-old, full-term, healthy female infant underwent a change in skin color from normal to red over one half of her body. The change in color persisted for a week.
? What is the diagnosis?

30/12/2025

A 38-year-old woman presented with a 12-month history of annular plaques on the forehead, cheeks, and neck. Skin biopsy revealed noncaseating epithelioid granulomas with sparse lymphocytic infiltration in the superficial dermis.

30/12/2025

A patient receiving adalimumab for rheumatoid arthritis had ulcerated plaques on the anterior and lateral aspects of the neck, upper chest, and nape and erythroderma on the dorsum of the hands, corresponding to areas of sun exposure, as well as swelling of the proximal interphalangeal hand joints bilaterally.

What is the diagnosis, and what would you do next?

https://ja.ma/4qNBF0n

28/12/2025

Crohn disease, ulcerative colitis, and psoriasis share an association with sacroiliitis and HLA-B27 positivity

28/12/2025

In patients with psoriatic arthritis, serum levels of
C-reactive protein (CRP) have been reported to be elevated (as compared to healthy controls), and elevated CRP levels represent a risk factor for
the development of cardiovascular disease.

28/12/2025

It has been shown that psoriatic patients who have had >200 PUVA treatments are at increased risk for the development of skin cancers, especially squamous cell carcinomas (SCCs). Of note, the use of cyclosporine in patients previously treated with PUVA significantly increases the number and rate of appearance of SCCs. Lastly, there is controversy as to whether PUVA_ treated patients have an increased risk of cutaneous melanoma.

The presence of neutrophils in the epidermis, either in spongiform pustules of Kogoj or in microabscesses of Munro, is a...
28/12/2025

The presence of neutrophils in the epidermis, either in spongiform pustules of Kogoj or in microabscesses of Munro, is a typical histopathologic feature of psoriasis, especially acute or pustular forms.

28/12/2025

More recently, greater insights into the genetics of pustular psoriasis have been made. In patients with generalized pustular psoriasis, several
groups identified homozygous or compound heterozygous loss-offunction mutations in IL36RN, which encodes the IL-36 receptor antagonist.
Patients with the autoinflammatory disorder DITRA (deficiency of IL-36 receptor antagonist) present with widespread psoriasiform plaques whose edges contain sterile pustules.

Based upon susceptibility loci and transcriptomics, a significant IL-36 signature was also observed in patients with plaque psoriasis.

28/12/2025

What is the diagnosis?

28/12/2025

Psoriasis patients have higher prevalence of metabolic syndrome.The combination of obesity, impaired glucose regulation, hypertriglyceridemia, reduced high-density lipoprotein, and hypertension is known as metabolic syndrome.

28/12/2025

☆☆Drug induced psoriasis☆☆

◾️-Short 12 weeks===》Lithium & B-blockers.

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